5,15-dibromoporphin | 85416-22-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: 5,15-dibromoporphin
• CAS: 85416-22-4
• 化学式: C₂₀H₁₂Br₂N₄
• 分子量: 468.15
• InChiKey: YFCLPQRMZIHGPQ-MCPZTIHVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.18
• 重原子数：
  26.0
• 可旋转键数：
  0.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  57.36
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  (1H-吡咯-2-基)-甲醇 在 溴 作用下， 以 氯仿 为溶剂， 反应 24.08h， 生成 5,15-dibromoporphin
  参考文献：
  名称：

  溴卟啉的研究

  摘要：

  描述了2-溴卟啉，5-溴卟啉，5,15-二溴卟啉和5、10、15-三溴卟啉的合成和表征。报道了用多种溴化剂获得的溴卟啉的产率。测量了光谱性质，并将其与化学性质一起作为卟啉中优选的离域途径的证据。

  DOI：

  10.1016/0040-4020(84)80019-8

文献信息

• Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same
  申请人：Zhang Peter X.

  公开号：US20050124596A1

  公开（公告）日：2005-06-09

  Novel methods of synthesizing heteroatom-containing chiral porphyrins and chiral metalloporphyrins and the novel chiral porphyrins and chiral metalloporphyrins themselves are disclosed. Metal complexes of the chiral porphyrins are prepared in high yields and shown to be active catalysts for highly enantioselective and diastereoselective cyclopropanation, aziridination, and epoxidation of alkenes under a practical one-pot protocol.

  揭示了合成含杂原子手性卟啉和手性金属卟啉的新方法，以及这些新型手性卟啉和手性金属卟啉本身。手性卟啉的金属配合物以高产率制备，并被证明是高度对映选择性和顺反异构选择性的催化剂，可在实用的一锅法协议下用于烯烃的环丙烷化、环氧化和环氧化反应。
• Cobalt-based catalysts for the cyclization of alkenes
  申请人：Zhang Peter X.

  公开号：US20060030718A1

  公开（公告）日：2006-02-09

  Metal-ligand complexes, including cobalt-ligand complexes, such as a cobalt-porphyrin complex, and their use as catalysts in the cyclization of alkenes.

  金属配合物，包括钴配体配合物，如钴卟啉配合物，以及它们在烯烃环化反应中作为催化剂的使用。
• Haloporphyrins and their preparation
  申请人：SUN COMPANY, INC. (R&M)

  公开号：EP0700915A1

  公开（公告）日：1996-03-13

  The invention provides novel catalyst compositions, useful in the oxidation of hydrocarbons with air or oxygen to form hydroxy-group containing compounds and in the decomposition of hydroperoxides to form hydroxy-group containing compounds. The catalysts comprise transition metal complexes of a porphyrin ring having 1 to 12 halogen substituents on the porphyrin ring, at least one of said halogens being in a meso position and/or the catalyst containing no aryl group in a meso position., The compositions are prepared by halogenating a transition metal complex of a porphyrin. In one embodiment, a complex of a porphyrin with a metal whose porphyrin complexes are not active for oxidation of hydrocarbons is halogenated, thereby to obtain a haloporphyrin complex of that metal, the metal is removed from the haloporphyrin complex to obtain the free base form of the haloporphyrin, and a metal such as iron whose porphyrin complexes are active for oxidation of hydrocarbons and for the decomposition of alkyl hydroperoxides is complexed with the free base to obtain an active catalyst for oxidation of hydrocarbons and decomposition of alkyl hydroperoxides.

  本发明提供了新型催化剂组合物，可用于碳氢化合物与空气或氧气的氧化反应以形成含羟基化合物，以及氢过氧化物的分解反应以形成含羟基化合物。这些催化剂包括在卟啉环上具有 1 至 12 个卤素取代基的卟啉环过渡金属络合物，其中至少一个卤素位于中间位置，和/或催化剂在中间位置不含芳基。在一个实施方案中，将卟啉与一种金属的络合物卤化，该金属的卟啉络合物对碳氢化合物的氧化没有活性，从而得到该金属的卤代卟啉络合物，将该金属从卤代卟啉络合物中除去，得到卤代卟啉的游离碱形式、将卟啉络合物对碳氢化合物的氧化和烷基氢过氧化物的分解具有活性的金属（如铁）与游离碱络合，得到一种对碳氢化合物的氧化和烷基氢过氧化物的分解具有活性的催化剂。
• Reactions catalyzed by haloporphyrins
  申请人：SUN COMPANY, INC. (R&M)

  公开号：EP0704447A1

  公开（公告）日：1996-04-03

  The invention provides novel methods for the oxidation of hydrocarbons with oxygen-containing gas to form hydroxy-group containing compounds and for the decomposition of hydroperoxides to form hydroxygroup containing compounds. The catalysts used in the methods of the invention comprise transition metal complexes of a porphyrin ring having 1 to 12 halogen substituents on the porphyrin ring, at least one of said halogens being in a meso position and/or the catalyst containing no aryl group in a meso position. The catalyst compositions are prepared by halogenating a transition metal complex of a porphyrin. In one embodiment, a complex of a porphyrin with a metal whose porphyrin complexes are not active for oxidation of alkanes is halogenated, thereby to obtain a haloporphyrin complex of that metal, the metal is removed from the haloporphyrin complex to obtain the free base form of the haloporphyrin, and a metal such as iron whose porphyrin complexes are active for oxidation of alkanes and for the decomposition of alkyl hydroperoxides is complexed with the free base to obtain an active catalyst for oxidation of alkanes and decomposition of alkyl hydroperoxides.

  本发明提供了用含氧气体氧化碳氢化合物以形成含羟基化合物和分解氢过氧化物以形成含羟基化合物的新方法。本发明方法中使用的催化剂包括在卟啉环上具有 1 至 12 个卤素取代基的卟啉环过渡金属配合物，所述卤素中至少有一个位于中间位置，和/或催化剂在中间位置不含芳基。催化剂组合物是通过卤化卟啉的过渡金属络合物制备的。在一个实施方案中，将卟啉与一种其卟啉络合物对烷烃氧化无活性的金属的络合物卤化，从而得到该金属的卤代卟啉络合物，再将该金属从卤代卟啉络合物中去除，得到卤代卟啉的游离碱形式、将卟啉络合物对烷烃氧化和烷基氢过氧化物分解具有活性的铁等金属与游离碱络合，得到烷烃氧化和烷基氢过氧化物分解的活性催化剂。
• Nudy, Louis R.; Coffey, Joan C.; Longo, Frederick R., Journal of Heterocyclic Chemistry, 1982, vol. 19, p. 1589 - 1590
  作者：Nudy, Louis R.、Coffey, Joan C.、Longo, Frederick R.、Kim, Jean B.

  DOI：——

  日期：——