sorboyloxy-4 benzoate de methyle | 88973-90-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: sorboyloxy-4 benzoate de methyle
• 英文别名: 4-hexa-2t,4t-dienoyloxy-benzoic acid methyl ester；4-Sorboyloxy-benzoesaeure-methylester；4-Hexa-2t,4t-dienoyloxy-benzoesaeure-methylester；methyl 4-[(2E,4E)-hexa-2,4-dienoyl]oxybenzoate
• CAS: 88973-90-4
• 化学式: C₁₄H₁₄O₄
• 分子量: 246.263
• InChiKey: KTSWYSHQQIRRDI-VNKDHWASSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  对羟基苯甲酸甲酯 、 山梨酸氯化物 在 sodium hydride 作用下， 以 N,N-二甲基甲酰胺 、 paraffin 、 苯 为溶剂， 反应 2.17h， 以77%的产率得到sorboyloxy-4 benzoate de methyle
  参考文献：
  名称：

  Le Baut; Sparfel; Clairc, European Journal of Medicinal Chemistry, 1983, vol. 18, # 5, p. 441 - 445

  摘要：

  DOI：

文献信息

• Cronk et al., 1959, vol. 48, p. 455
  作者：Cronk et al.

  DOI：——

  日期：——
• LE, BAUT, G.;SPARFEL, L.;CLAIRC, C.;FLOCH, R.;BENAZET, F.;LACROIX, L.;LER+, EUR. J. MED. CHEM., 1983, 18, N 5, 441-445
  作者：LE, BAUT, G.、SPARFEL, L.、CLAIRC, C.、FLOCH, R.、BENAZET, F.、LACROIX, L.、LER+

  DOI：——

  日期：——
• Device for administering a dose of an analgesic liquid to an infant
  申请人：Agarwal Raj

  公开号：US20100249751A1

  公开（公告）日：2010-09-30

  A disposable article of manufacture, adapted for use by an infant to provide an analgesic effect, comprises: (a) a dispensing device having a container portion for holding an analgesic liquid and a contiguous nipple-shaped portion designed to be sucked by an infant, for pacifying the infant while at the same time dispensing and administering the analgesic liquid to the infant through at least one opening in the nipple-shaped portion; and (b) a dose of the analgesic liquid, in sterile form, disposed in the container portion and/or the nipple-shaped portion of the dispensing device, the dose having a having a volume in the range of 1 to 10 ml and the analgesic liquid consisting essentially of a water solution of sucrose and having a sucrose concentration in the range of 20 to 60% w/v and (c) a removable article for sealing the opening in the nipple-shaped portion and the dose of analgesic liquid, thereby to prevent entry of bacteria into the analgesic liquid and prevent discharge of the analgesic liquid when the dispensing device is not in use.
• Le Baut; Sparfel; Clairc, European Journal of Medicinal Chemistry, 1983, vol. 18, # 5, p. 441 - 445
  作者：Le Baut、Sparfel、Clairc、et al.

  DOI：——

  日期：——