3-O-(6-deoxy-6-sulfo-α-D-mannopyranosyl)-1-O-palmitoyl-glycerol sodium salt | 534574-99-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 3-O-(6-deoxy-6-sulfo-α-D-mannopyranosyl)-1-O-palmitoyl-glycerol sodium salt
• 英文别名: sodium;[(2S,3S,4S,5S,6S)-6-(3-hexadecanoyloxy-2-hydroxypropoxy)-3,4,5-trihydroxyoxan-2-yl]methanesulfonate
• CAS: 534574-99-7
• 化学式: C₂₅H₄₇O₁₁S*Na
• 分子量: 578.697
• InChiKey: FRZXJLKJTDWXCC-DSGSGBCTSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.25
• 重原子数：
  38
• 可旋转键数：
  21
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  191
• 氢给体数：
  4
• 氢受体数：
  11

文献信息

• Novel sulforhamnosylacylglycerol derivatives and use thereof as medicaments
  申请人：TOYO SUISAN KAISHA, LTD.

  公开号：US20020022597A1

  公开（公告）日：2002-02-21

  Novel sulforhamnosylacylglycerol derivatives represented by General Formula (1): 1 where R 101 represents an acyl residue of a higher fatty acid and R 102 represents a hydrogen atom or an acyl residue of a higher fatty acid. The derivatives represented by General formula (1) are useful as, a DNA polymerase inhibitor and an anticancer agent.

  通式（1）所代表的新型硫代酸酯基甘油衍生物：其中，R101代表高级脂肪酸的酰基残基，R102代表氢原子或高级脂肪酸的酰基残基。通式（1）所代表的衍生物可用作DNA聚合酶抑制剂和抗癌剂。
• NOVEL SULFORHAMNOSYLACYLGLYCEROL DERIVATIVES AND UTILIZATION THEREOF AS DRUGS
  申请人：Toyo Suisan Kaisha, Ltd.

  公开号：EP1164139A1

  公开（公告）日：2001-12-19

  Novel sulforhamnosylacylglycerol derivatives represented by General Formula (1): where R101 represents an acyl residue of a higher fatty acid and R102 represents a hydrogen atom or an acyl residue of a higher fatty acid. The derivatives represented by General formula (1) are useful as a DNA polymerase inhibitor and an anticancer agent.

  由通式(1)代表的新型磺基鼠李糖酰甘油衍生物： 其中 R101 代表高级脂肪酸的酰基残基，R102 代表氢原子或高级脂肪酸的酰基残基。通式（1）代表的衍生物可用作 DNA 聚合酶抑制剂和抗癌剂。
• NOVEL SULFORHAMNOSYLACYLGLYCEROL DERIVATIVES AND USE THEREOF AS MEDICAMENTS
  申请人：Toyo Suisan Kaisha, Ltd.

  公开号：EP1164139B1

  公开（公告）日：2003-07-09
• US6759522B2
  申请人：——

  公开号：US6759522B2

  公开（公告）日：2004-07-06