N-[chloro(dimethyl)silyl]-2,6-dimethyl-N-trimethylsilylaniline | 877174-89-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[chloro(dimethyl)silyl]-2,6-dimethyl-N-trimethylsilylaniline
• CAS: 877174-89-5
• 化学式: C₁₃H₂₄ClNSi₂
• 分子量: 285.964
• InChiKey: RJJRBWMRPCPZGL-UHFFFAOYSA-N

物化性质

• 沸点：
  283.8±40.0 °C(Predicted)
• 密度：
  0.978±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.89
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-[chloro(dimethyl)silyl]-2,6-dimethyl-N-trimethylsilylaniline 在 水 、 碳酸氢铵 、 sodium chloride 作用下， 以 乙醚 为溶剂， 反应 2.0h， 以76%的产率得到N-[hydroxy(dimethyl)silyl]-2,6-dimethyl-N-trimethylsilylaniline
  参考文献：
  名称：

  N ‐Bonded Monosilanols: Synthesis and Characterization of ArN(SiMe ₃ )SiMe ₂ Cl and ArN(SiMe ₃ )SiMe ₂ OH (Ar = C ₆ H ₅ , 2,6‐Me ₂ C ₆ H ₃ ,2,6‐ i Pr ₂ C ₆ H ₃ )

  摘要：

  AbstractBy the use of aniline and the sterically hindered aromatic primary amines, 2,6‐Me2C6H3NH2 and 2,6‐iPr2C6H3NH2, N‐bonded monochlorosilanes, ArN(SiMe3)SiMe2Cl [Ar = C6H5 (1a), Ar = 2,6‐Me2C6H3 (1b) and Ar = 2,6‐iPr2C6H3 (1c)] have been prepared by a sequential deprotonation at the nitrogen followed by reaction with silyl chlorides. Hydrolysis of the N‐bonded monochlorosilanes afforded the N‐bonded monosilanols ArN(SiMe3)SiMe2OH [Ar = C6H5 (2a), Ar = 2,6‐Me2C6H3 (2b) and Ar = 2,6‐iPr2C6H3 (2c)]. The X‐ray crystal structure of 1c reveals a positional disorder of the Cl and CH3 substituents on silicon. The X‐ray crystal structure of 2c shows that it is involved in an intermolecular O–H···O hydrogen bonding in the solid state to afford a dimeric structure containing the O2H2 ring. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)

  DOI：

  10.1002/ejic.200401013
• 作为产物：
  描述：

  2,6-二甲基苯胺 在 正丁基锂 作用下， 以 乙醚 为溶剂， 反应 4.0h， 生成 N-[chloro(dimethyl)silyl]-2,6-dimethyl-N-trimethylsilylaniline
  参考文献：
  名称：

  N ‐Bonded Monosilanols: Synthesis and Characterization of ArN(SiMe ₃ )SiMe ₂ Cl and ArN(SiMe ₃ )SiMe ₂ OH (Ar = C ₆ H ₅ , 2,6‐Me ₂ C ₆ H ₃ ,2,6‐ i Pr ₂ C ₆ H ₃ )

  摘要：

  AbstractBy the use of aniline and the sterically hindered aromatic primary amines, 2,6‐Me2C6H3NH2 and 2,6‐iPr2C6H3NH2, N‐bonded monochlorosilanes, ArN(SiMe3)SiMe2Cl [Ar = C6H5 (1a), Ar = 2,6‐Me2C6H3 (1b) and Ar = 2,6‐iPr2C6H3 (1c)] have been prepared by a sequential deprotonation at the nitrogen followed by reaction with silyl chlorides. Hydrolysis of the N‐bonded monochlorosilanes afforded the N‐bonded monosilanols ArN(SiMe3)SiMe2OH [Ar = C6H5 (2a), Ar = 2,6‐Me2C6H3 (2b) and Ar = 2,6‐iPr2C6H3 (2c)]. The X‐ray crystal structure of 1c reveals a positional disorder of the Cl and CH3 substituents on silicon. The X‐ray crystal structure of 2c shows that it is involved in an intermolecular O–H···O hydrogen bonding in the solid state to afford a dimeric structure containing the O2H2 ring. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)

  DOI：

  10.1002/ejic.200401013