1,2-cis-diphenoxyethylene | 73421-47-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,2-cis-diphenoxyethylene
• 英文别名: cis-1,2-diphenoxyethene；[(Z)-2-phenoxyethenoxy]benzene
• CAS: 73421-47-3
• 化学式: C₁₄H₁₂O₂
• 分子量: 212.248
• InChiKey: BMUKUQUGQLFWDZ-QXMHVHEDSA-N

物化性质

• 熔点：
  64-66 °C
• 沸点：
  295.8±23.0 °C(Predicted)
• 密度：
  1.105±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,2-cis-diphenoxyethylene 在 5-(4'-hydroxyphenyl)-10,15,20-triphenylporphyrin 作用下， 反应 0.25h， 以80%的产率得到甲酸苯酯
  参考文献：
  名称：

  Low energy light-triggered oxidative cleavage of olefins

  摘要：

  A series of substituted olefins were tested for their reactivity with singlet oxygen as a singlet oxygen-mediated cleavable linker. Low intensity light of 200 mW/cm(2) was irradiated to the solution of an olefin and 5,10,15-triphenyl-20-(4-hydroxyphenyl)-21H,23H-porphyrin under atmospheric condition, Among the tested olefins, 1,2-cis-diphenoxyethylene reacted fast with singlet oxygen, >80% within 15 min yielding a stoichiometric conversion to aldehyde product without ally side reactions. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.12.069
• 作为产物：
  描述：

  trans-1,2-bis(4-bromophenoxy)ethene 在 正丁基锂 、 溴 、 锌 作用下， 以 乙醚 、 乙醇 、 正己烷 、 氯仿 、 水 为溶剂， 反应 3.33h， 生成 1,2-cis-diphenoxyethylene
  参考文献：
  名称：

  Synthesis of cis- and trans-1,2-Diphenoxyethenes and p,p‘-Disubstituted Diaryloxyethenes

  摘要：

  DOI：

  10.1021/jo9812577

文献信息

• Highly Active Cross-Metathesis of Tetrafluoroethylene with a Seven-Membered N-Heterocyclic-Carbene–Ruthenium Catalyst
  作者：Kenta Mori、Midori Akiyama、Ko Inada、Yutaka Imamura、Yuichiro Ishibashi、Yusuke Takahira、Kyoko Nozaki、Takashi Okazoe

  DOI：10.1021/jacs.1c10574

  日期：2021.12.15

  A drastic increase in catalyst turnover number (TON) was accomplished in the cross-metathesis of tetrafluoroethylene (TFE) and vinyl ethers. Under a continuous flow of TFE, catalyst Ru7, which contains a seven-membered N-heterocyclic carbene (NHC) ligand, reached a TON of 4100; this is 2 orders of magnitude higher than the highest hitherto reported value. Mechanistic studies revealed that the expanded

  在四氟乙烯 (TFE) 和乙烯基醚的交叉复分解中实现了催化剂周转数 (TON) 的急剧增加。在 TFE 的连续流动下，含有七元 N-杂环卡宾 (NHC) 配体的催化剂Ru7的 TON 达到 4100；这比迄今为止报告的最高值高出 2 个数量级。机理研究表明，扩展的 NHC 成功地破坏了具有二氟卡宾结构的稳定中间体，从而强烈促进了反应。
• SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF
  申请人：The Board of Regents of the University of Oklahoma

  公开号：US20150165026A1

  公开（公告）日：2015-06-18

  Activatable compositions that include at least one functional moiety and at least one cleavable linker directly or indirectly linked to the at least one functional moiety are disclosed. The at least one functional moiety is inactive when linked to the linker and activated upon cleavage of the linker. Methods of production and use of the activatable composition are also disclosed.

  本发明揭示了包括至少一个功能性基团和至少一个可断裂连接基团的可活化组合物，该可断裂连接基团直接或间接连接至少一个功能性基团。当连接到连接基团时，至少一个功能性基团是不活性的，并在连接基团被断裂时被激活。本发明还揭示了制备和使用该可活化组合物的方法。
• Singlet Oxygen-Labile Linkers and Methods of Production and Use Thereof
  申请人：The Board of Regents of the University of Oklahoma

  公开号：US20170014510A1

  公开（公告）日：2017-01-19

  Activatable compositions that include at least one functional moiety and at least one cleavable linker directly or indirectly linked to the at least one functional moiety are disclosed. The at least one functional moiety is inactive when linked to the linker and activated upon cleavage of the linker. Methods of production and use of the activatable composition are also disclosed.
• US9393306B2
  申请人：——

  公开号：US9393306B2

  公开（公告）日：2016-07-19
• US9839690B2
  申请人：——

  公开号：US9839690B2

  公开（公告）日：2017-12-12