Et2MeSiP(O)Ph2 | 1070897-70-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Et2MeSiP(O)Ph2
• CAS: 1070897-70-9
• 化学式: C₁₇H₂₃OPSi
• 分子量: 302.428
• InChiKey: JAMFFICAENSVFW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.62
• 重原子数：
  20.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  17.07
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  二乙基甲基硅烷 、 四苯基二膦 在 四(三苯基膦)钯 作用下， 以 氘代苯 为溶剂， 反应 18.0h， 生成 Et2MeSiP(O)Ph2
  参考文献：
  名称：

  A Highly Regioselective Palladium-Catalyzed Hydrophosphination of Alkynes Using a Diphosphine−Hydrosilane Binary System

  摘要：

  A novel transition-metal-catalyzed hydrophosphination of terminal alkynes using a diphosphine-hydrosilane binary system takes place regioselectively to provide vinylic phosphines, which undergo air oxidation during workup, affording the corresponding vinylphosphine oxides in good yields. In this hydrophosphination, hydrosilanes act as a useful hydrogen source, and furthermore, small amounts of oxygen is required to accomplish the reaction efficiently.

  DOI：

  10.1021/jo801267y

文献信息

• Rhodium-Catalyzed <i>Anti</i>-Markovnikov–Type Hydrophosphination of Terminal Alkynes with Diphosphines and Hydrosilanes in the Presence of Oxygen
  作者：Shin-ichi Kawaguchi、Mao Kotani、Takashi Ohe、Shoko Nagata、Akihiro Nomoto、Motohiro Sonoda、Akiya Ogawa

  DOI：10.1080/10426501003773423

  日期：2010.5.27

  A novel rhodium(I)-catalyzed hydrophosphination of terminal alkynes with diphosphines and hydrosilanes takes place regioselectively in the presence of small amounts of oxygen. After air-oxidation during workups, the corresponding anti-Markovnikov–type vinylic phosphine oxides were obtained in good yields.

  末端炔烃与二膦和氢硅烷的新型铑（I）催化氢膦化反应在少量氧气存在下发生区域选择性。在后处理过程中进行空气氧化后，以良好的收率获得了相应的抗马尔科夫尼科夫型乙烯基氧化膦。