| 1315306-51-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• CAS: 1315306-51-4
• 化学式: C₁₁H₁₃N₂O₅PS
• 分子量: 316.274
• InChiKey: DELOSHWGUDOILK-UHFFFAOYSA-N

物化性质

• 沸点：
  496.8±45.0 °C(predicted)
• 密度：
  1.47±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

反应信息

• 作为产物：
  描述：

  在 sulfur 、 二乙胺 作用下， 以 乙醇 为溶剂， 生成 、
  参考文献：
  名称：

  Novel aminophosphonothiophene derivatives from β-keto-δ-carbethoxyphosphonates and phosphineoxides

  摘要：

  The reaction of -keto--carbethoxyphosphonates and phosphineoxides with active methylene nitriles leads to the corresponding phosphonoalkylidenes. Treatment of these compounds with sulfur, under the classical Gewald reaction conditions, gives a ca. 1:1 mixture of novel aminophosphonothiophene derivatives 3 and 3'. In order to improve the regioselectivity of the reaction, novel conditions have been developed for the Gewald condensation, in which we used an inorganic base NaH in THF as the solvent. These conditions afforded exclusively the 3-regioisomer in good yield. [image omitted].

  DOI：

  10.1080/17415993.2011.570763