| 1266339-36-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1266339-36-9
• 化学式: C₁₄H₁₄BrNO
• 分子量: 292.175
• InChiKey: NAFKGQLUYVBWLU-NSHDSACASA-N

反应信息

• 作为反应物：
  描述：

  在 nickel(II) chloride hexahydrate 、 三苯基膦 、 锌 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 3.0h， 以49%的产率得到
  参考文献：
  名称：

  Chiral copper–bipyridine complexes: Synthesis, characterization and mechanistic studies on asymmetric cyclopropanation

  摘要：

  Chiral bipyridine ligands of different steric properties when reacted with CuCl(2) formed orange, yellow or green solids of new copper(II) complexes, [Cu(L)Cl(2)] (L = 12-6), in good yield. Together with Ku(L1)Cl(2)], these complexes were characterized in solution by UV-Vis spectroscopy and cyclic voltammetry. The complexes give d-d transitions between 860 and 970 nm, and exhibit one quasi-reversible Cu(II)/Cu(I) couple between +0.405 V and +0.516 V versus NHE. Two of the copper(II) complexes, [Cu(L5)Cl(2)] and [Cu(L6)Cl(2)], and a copper(I) complex of L1, [Cu(L1)01, were characterized by X-ray crystallography. The triflate derivatives of both the Cu(I) and Cu(II) complexes are active catalysts towards the cyclopropanation of ethyl diazoacetate with styrene. The asymmetric induction suffers when the size difference between the alkyl and alkoxyl groups was minimized. The mechanism of the cyclopropanation was studied with kinetic and competition experiments. The rate is first order in catalyst and ethyl diazoacetate, inverse order with styrene and is strongly affected by the counterion. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2010.10.021