Synthesis of 2-substituted benzimidazoles by iodine-mediated condensation of orthoesters with 1,2-phenylenediamines
作者:Zhan-Hui Zhang、Jian-Jiong Li、Yuan-Zhe Gao、Yu-Heng Liu
DOI:10.1002/jhet.5570440642
日期:2007.11
Iodine was found to be an efficient catalyst for the synthesis of 2-substitutedbenzimidazoles by the condensation of orthoesters and 1,2-phenylenediamines in good to excellent yields under mild reaction conditions.