2-fluoro-6-[(4,6-dimethoxypyrimidin-2-yl)methyl]-N-difluoromethanesulfon-anilide | 866128-69-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-fluoro-6-[(4,6-dimethoxypyrimidin-2-yl)methyl]-N-difluoromethanesulfon-anilide
• 英文别名: 2-fluoro-6-[(4,6-dimethoxytriazin-2-yl)methyl]-N-difluoromethanesulfonanilide；N-{2-fluoro-6-[(4,6-dimethoxy-pyrimidin-2-yl)methyl]phenyl}-1,1-difluoromethanesulfonamide；N-[2-[(4,6-dimethoxypyrimidin-2-yl)methyl]-6-fluorophenyl]-1,1-difluoromethanesulfonamide
• CAS: 866128-69-0
• 化学式: C₁₄H₁₄F₃N₃O₄S
• 分子量: 377.344
• InChiKey: VMVIXTUUWBPBAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  98.8
• 氢给体数：
  1
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  2-fluoro-6-[(4,6-dimethoxypyrimidin-2-yl)methyl]-N-difluoromethanesulfon-anilide 、 乙酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 以89%的产率得到2-fluoro-6-[(4,6-dimethoxypyrimidin-2-yl)methyl]-N-acetyl-N-difluoromethanesulfonanilide
  参考文献：
  名称：

  [EN] A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE
  [FR] UTILISATION DE SULFONANILIDES COMME FONGICIDES POUR L'AGRICULTURE ET L'HORTICULTURE

  摘要：

  式（I）的化合物，其中Z代表C-R7或N，而R5代表可以选择性取代的烷基，烯基，炔基，环烷基或烷氧羰基氨基，对农业和园艺真菌杀菌剂具有用处。

  公开号：

  WO2006008159A1

文献信息

• USE OF SULFONANILIDE COMPOUNDS AS HERBICIDE
  申请人：ARAKI KOICHI

  公开号：US20090062536A1

  公开（公告）日：2009-03-05

  A herbicide comprising as an active ingredient a sulfonanilide compound represented by the formula: wherein, R1 represents CHF 2 or CH 2 CF 3 ; R2 represents hydrogen, C1-3 alkyl, 3-propenyl, or 3-propynyl; R3 represents hydrogen; R4 represents hydrogen, hydroxy, or methylthio, or R3 and R4, together with a carbon atom to which they are bonded, may form C═O; R5 represents halogen or methyl; X represents methoxy or chlorine; and Z represents CH or N; with the proviso that, (i) when R1 represents CH 2 CF 3 , R2 represents hydrogen, R5 represents bromine or iodine, X represents methoxy, and Z represents CH, (ii) when R1 represents CHF 2 and X represents methoxy, R5 represents bromine or iodine, Z represents N, and R2 represents C1-3 alkyl, 3-propenyl, or 3-propynyl, (iii) when R1 represents CHF 2 and X represents chlorine, Z represents CH.

  一种除草剂，其活性成分为由以下公式表示的磺酰苯胺化合物：其中，R1代表CHF2或CH2CF3; R2代表氢、C1-3烷基、3-丙烯基或3-丙炔基; R3代表氢; R4代表氢、羟基或甲硫基，或R3和R4与它们连接的碳原子一起形成C═O; R5代表卤素或甲基; X代表甲氧基或氯; Z代表CH或N; 前提是，(i) 当R1代表CH2CF3时，R2代表氢，R5代表溴或碘，X代表甲氧基，Z代表CH，(ii) 当R1代表 且X代表甲氧基，R5代表溴或碘，Z代表N，R2代表C1-3烷基、3-丙烯基或3-丙炔基，(iii) 当R1代表 且X代表氯，Z代表CH。
• DIFLUOROMETHANESFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES
  申请人：ARAKI Koichi

  公开号：US20080312084A1

  公开（公告）日：2008-12-18

  Novel difluoromethanesulfonamide derivatives of the formula (I) Difluoromethanesulfonamide derivatives represented by the formula wherein X represents halogen, Y represents CH or N, R 1 represents hydrogen, and R 2 represents hydrogen or hydroxy, or R 1 and R 2 together may form C═O with the carbon atom to which they are bonded, and their use as herbicide for paddy field weeds.

  化合物的式子为(I)，该化合物为新型二氟甲磺酰胺衍生物，式中X代表卤素，Y代表CH或N，R1代表氢原子，R2代表氢原子或羟基，或者R1和R2共同形成与它们结合的碳原子的C═O键。该化合物可作为稻田杂草的除草剂。
• DIFLUOROMETHANESULFONYL ANILIDE DERIVATIVES USEFUL AS HERBICIDES
  申请人：Bayer CropScience AG

  公开号：EP1750510B1

  公开（公告）日：2007-08-22
• A USE OF SULFONANILIDES AS AGRICULTURAL AND HORTICULTURAL FUNGICIDE
  申请人：Bayer CropScience Aktiengesellschaft

  公开号：EP1773124B1

  公开（公告）日：2012-08-22
• Difluoromethanesulfonyl anilide derivatives useful as herbicides
  申请人：Araki Koichi

  公开号：US20070197390A1

  公开（公告）日：2007-08-23

  Novel difluoromethanesulfonamide derivatives of the formula (I) Difluoromethanesulfonamide derivatives represented by the formula wherein X represents halogen, Y represents CH or N, R 1 represents hydrogen, and R 2 represents hydrogen or hydroxy, or R 1 and R 2 together may form C=O with the carbon atom to which they are bonded, and their use as herbicide for paddy field weeds.