1-methyl-3,4-bis(methylthio)-1H-pyrrole-2,5-dione | 32774-54-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 1-methyl-3,4-bis(methylthio)-1H-pyrrole-2,5-dione
• 英文别名: 1-Methyl-3,4-bis(methylsulfanyl)pyrrole-2,5-dione
• CAS: 32774-54-2
• 化学式: C₇H₉NO₂S₂
• 分子量: 203.286
• InChiKey: WCVRSMTYHINVJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  88
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2,3-二氯-N-甲基马来酰亚胺顺丁烯二酰亚胺 、 sodium thiomethoxide 在 sodium acetate 作用下， 以 甲醇 为溶剂， 反应 1.0h， 以53%的产率得到1-methyl-3,4-bis(methylthio)-1H-pyrrole-2,5-dione
  参考文献：
  名称：

  [EN] 3,4-DISUBSTITUTED PYRROLE 2,5-DIONES AND THEIR USE AS FUNGICIDES
  [FR] (PYRROLE DISUBSTITUÉ EN 3,4)2,5-DIONES ET LEUR UTILISATION COMME FONGICIDES

  摘要：

  本发明涉及使用如描述中定义的式I的3,4-二取代吡咯-2,5-二酮来控制植物病原真菌。此外，本发明还涉及式I的新化合物。

  公开号：

  WO2012143468A1

文献信息

• 3,4-disubstituted pyrrole 2,5-diones and their use as fungicides
  申请人：Riggs Richard

  公开号：US20140045689A1

  公开（公告）日：2014-02-13

  The present invention relates to the use of 3,4-disubstituted pyrrole 2,5-diones of the formula I as defined in the description for controlling phytopathogenic fungi. Further the invention relates to novel compounds of the formula I.

  本发明涉及使用式I中描述的3,4-二取代吡咯-2,5-二酮来控制植物病原真菌。此外，本发明还涉及式I的新化合物。
• 3,4-DISUBSTITUTED PYRROLE 2,5-DIONES AND THEIR USE AS FUNGICIDES
  申请人：BASF SE

  公开号：EP2699090A1

  公开（公告）日：2014-02-26
• TRISPECIFIC BINDING MOLECULES AGAINST CANCERS AND USES THEREOF
  申请人：GRANDA Brian

  公开号：US20210163620A1

  公开（公告）日：2021-06-03

  The present disclosure provides multispecific binding molecules that specifically bind to a first tumor-associated antigen that is expressed on cancerous B cells, a second tumor-associated antigen that is expressed on cancerous B cells, and a component of a human T-cell receptor complex, conjugates comprising the trispecific binding molecules, and pharmaceutical compositions comprising the multispecific binding molecules and the conjugates. The disclosure further provides methods of using the multispecific binding molecules to treat cancers that express the tumor-associated antigens. The disclosure yet further provides recombinant host cells engineered to express the multispecific binding molecules and methods of producing the multispecific binding molecules by culturing the host cells under conditions in which the multispecific binding molecules are expressed.
• [EN] 3,4-DISUBSTITUTED PYRROLE 2,5-DIONES AND THEIR USE AS FUNGICIDES<br/>[FR] (PYRROLE DISUBSTITUÉ EN 3,4)2,5-DIONES ET LEUR UTILISATION COMME FONGICIDES
  申请人：BASF SE

  公开号：WO2012143468A1

  公开（公告）日：2012-10-26

  The present invention relates to the use of 3,4-disubstituted pyrrole 2,5-diones of the formula I as defined in the description for controlling phytopathogenic fungi. Further the invention relates to novel compounds of the formula I.

  本发明涉及使用如描述中定义的式I的3,4-二取代吡咯-2,5-二酮来控制植物病原真菌。此外，本发明还涉及式I的新化合物。