Eu(III)(morin(1-))3 | 939125-94-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 2-芳基苯并呋喃类黄酮
• 英文名称: Eu(III)(morin(1-))3
• CAS: 939125-94-7
• 化学式: C₄₅H₂₇EuO₂₁
• 分子量: 1055.66
• InChiKey: KEVUYRMHIKCICR-UHFFFAOYSA-K

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  europium(III) oxide 、 桑色素 在 盐酸 、 Tris-HCl buffer 作用下， 以 甲醇 、 水 为溶剂， 生成 Eu(III)(morin(1-))3
  参考文献：
  名称：

  Spectroscopic studies on the interaction of morin–Eu(III) complex with calf thymus DNA

  摘要：

  The interaction between morin-Eu(III) complex and calf thymus DNA in physiological buffer (pH 7.4) was investigated using UV-vis spectrophotometry, fluorescence spectroscopy, viscosity measurements and DNA melting techniques. Hypochromicity and red shift of the absorption spectra of morin-Eu(III) complex were observed in the presence of DNA, and the fluorescence intensity of morin-Eu(III) complex was greatly enhanced with the addition of DNA. Moreover, fluorescence quenching and blue shift of the emission peak were seen in the DNA-ethidium bromide (EB) system when morin-Eu(III) complex was added. The relative viscosity of DNA increased with the addition of morin-Eu(ill) complex, whereas the value of melting temperature of DNA-EB system decreased in the presence of morin-Eu(III) complex. All these results indicated that morin-Eu(III) complex can bind to DNA and the major binding mode is intercalative binding. The 3:1 morin:Eu(III) complex (estimated binding constant = 2.36 x 10(6) L mol(-1)) is stabilized by intercalation into the DNA. The Calculated binding constants of morin-EU(III) complex with DNA at 292, 301 and 310 K were 7.47 x 10(4), 8.89 x 10(4) and 1.13 x 10(5) L mol(-1), respectively. The thermodynamic parameters were also obtained: Delta H-0 was 20.14 kJ mol(-1) > 0 and Delta S-0 was 161.70 J mol(-1) K-1 > 0, suggesting that hydrophobic force plays a major role in the binding of morin Eu(III) complex to DNA. (c) 2009 Elsevier B.V, All rights reserved.

  DOI：

  10.1016/j.molstruc.2009.02.011