9-iodo-fluorene | 64421-01-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: 9-iodo-fluorene
• 英文别名: 9-Jod-fluoren；9-Iodfluoren；9-Jodfluoren；9-iodo-9H-fluorene
• CAS: 64421-01-8
• 化学式: C₁₃H₉I
• 分子量: 292.119
• InChiKey: YPZMUXQQEWJJSD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  9-iodo-fluorene 生成 9,9'-联芴
  参考文献：
  名称：

  Wanscheidt, Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1926, vol. 58, p. 72

  摘要：

  DOI：
• 作为产物：
  描述：

  9-溴芴 在 丙酮 、 sodium iodide 作用下， 生成 9-iodo-fluorene
  参考文献：
  名称：

  Wanscheidt, Chemische Berichte, 1926, vol. 59, p. 2099

  摘要：

  DOI：

文献信息

• [EN] COMPOUNDS USEFUL FOR PROMOTING PROTEIN DEGRADATION AND METHODS USING SAME<br/>[FR] COMPOSÉS UTILES POUR STIMULER LA DÉGRADATION DES PROTÉINES ET PROCÉDÉS UTILISANT CEUX-CI
  申请人：UNIV YALE

  公开号：WO2013170147A1

  公开（公告）日：2013-11-14

  The present invention includes compounds that act as degraders of a target protein, wherein degradation is independent of the class of the target protein or its localization. In one embodiment, the invention comprises a compound comprising a protein degradation moiety covalently bound to a linker, wherein the ClogP of the compound is equal to or higher than 1.5. The target protein contemplated within the invention comprises a posttranslational modified protein or intracellular protein. Compounds of the present invention may be used to treat disease states wherein protein degradation is a viable therapeutic approach, such as cancer or any sort of oxidative stress disease state.

  本发明包括作为目标蛋白质降解剂的化合物，其中降解与目标蛋白质的类别或其定位无关。在一种实施方式中，该发明包括一种化合物，其中蛋白质降解基团与连接剂共价结合，该化合物的ClogP等于或高于1.5。本发明中考虑的目标蛋白质包括后转录修饰蛋白质或细胞内蛋白质。本发明的化合物可用于治疗蛋白质降解是一种可行的治疗方法的疾病状态，如癌症或任何一种氧化应激疾病状态。
• Supported Salan Catalysts
  申请人：ExxonMobil Chemical Patents Inc.

  公开号：US20170096508A1

  公开（公告）日：2017-04-06

  A catalyst system including the reaction product of a fluorided support, an activator, and at least a first transition metal catalyst compound; methods of making such catalyst systems, polymerization processes using such catalyst systems, and polymers made therefrom.

  一个催化剂系统包括氟化支撑物、活化剂和至少一个第一过渡金属催化剂化合物的反应产物；制备这种催化剂系统的方法，使用这种催化剂系统的聚合过程以及由此制得的聚合物。
• Cyclopentadienyl-Substituted Salan Catalysts
  申请人：ExxonMobil Chemical Patents Inc.

  公开号：US20150166690A1

  公开（公告）日：2015-06-18

  A cyclopentadienyl-substituted Salan catalyst, a catalyst system comprising an activator and the cyclopentadienyl-substituted Salan catalyst, a process comprising contacting one or more olefins with the catalyst system, and polymers produced by the process are disclosed herein.

  本文公开了一种环戊二烯基取代的Salan催化剂，一种包括活化剂和环戊二烯基取代的Salan催化剂的催化剂体系，一种将一个或多个烯烃与催化剂体系接触的过程，以及由该过程产生的聚合物。
• LIGHT-EMITTING ELEMENT AND METHOD FOR MANUFACTURING SAME
  申请人：Sumitomo Chemical Company, Ltd.

  公开号：EP3306694A1

  公开（公告）日：2018-04-11

  To provide a light emitting device capable of emitting light at high luminance. A light emitting device comprising an anode, a cathode, a phosphorescent light emitting layer, an electron transporting layer (B) disposed between the cathode and the light emitting layer and adjacent to the cathode, and an electron transporting layer (A) disposed between the light emitting layer and the electron transporting layer (B) , wherein P (eV) which is the smallest work function of the metal material contained in an amount of 1% by weight or more in the cathode, Q (eV) which is the smallest electron affinity of the compound contained in an amount of 5% by weight or more in the light emitting layer, RA (eV) which is the smallest electron affinity of the compound contained in an amount of 5% by weight or more in the electron transporting layer (A) and RB (eV) which is the smallest electron affinity of the compound contained in an amount of 5% by weight or more in the electron transporting layer (B) satisfy the formulae (1A) to (4A) : P>3.5 Q<2.7 P>RB>Q RB>RA

  提供一种能以高亮度发光的发光器件。 发光器件包括 阳极 阴极 磷光发光层、 设置在阴极和发光层之间并邻近阴极的电子传输层 (B)，以及 位于发光层和电子传输层（B）之间的电子传输层（A）、 其中 P (eV)，即阴极中金属材料的最小功函数，其含量为阴极重量的 1%或以上、 Q (eV)，即发光层中所含化合物的最小电子亲和力，含量为 5%（按重量计）或更多、 RA（电子伏特）是电子传输层（A）中所含化合物的最小电子亲和力，其含量为 5%（按重量计）或更多；以及 RB（eV）是电子传输层（B）中所含化合物的最小电子亲和力，按重量计，含量为 5%或更多，满足式（1A）至（4A）：P>3.5 QRB>Q RB>RA
• WATER ABSORBENT RESIN PARTICLES AND METHOD FOR PRODUCING SAME
  申请人：SDP Global Co., Ltd.

  公开号：EP3357937A1

  公开（公告）日：2018-08-08

  Provided is a method for producing water-absorbent resin particles, which is capable of improving the gel strength for the purpose of achieving a good balance between the absorption under load and the rate of liquid permeation through gel. The present invention is a method for producing water-absorbent resin particles, which is characterized by comprising a step wherein a monomer composition containing a water-soluble vinyl monomer (a1) and/or a vinyl monomer (a2) that turns into a water-soluble vinyl monomer (a1) by means of hydrolysis and a crosslinking agent (b) is polymerized in the presence of at least one organic main group element compound selected from the group consisting of organic iodine compounds, organic tellurium compounds, organic antimony compounds, and organic bismuth compounds.

  本发明提供了一种生产吸水性树脂颗粒的方法，该方法能够提高凝胶强度，从而在负载下的吸收和液体通过凝胶的渗透率之间实现良好的平衡。本发明是一种生产吸水性树脂颗粒的方法，其特征在于包括以下步骤：将含有水溶性乙烯基单体（a1）和/或通过水解变成水溶性乙烯基单体（a1）的乙烯基单体（a2）和交联剂（b）的单体组合物在至少一种选自有机碘化合物、有机碲化合物、有机锑化合物和有机铋化合物的有机主族元素化合物存在下进行聚合。

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