(1R,2R)-N,N′-bis[(5-methylfuran-2-yl)methylidene]cyclohexane-1,2-diamine | 1598408-94-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: (1R,2R)-N,N′-bis[(5-methylfuran-2-yl)methylidene]cyclohexane-1,2-diamine
• 英文别名: 1-(5-methylfuran-2-yl)-N-[(1R,2R)-2-[(5-methylfuran-2-yl)methylideneamino]cyclohexyl]methanimine
• CAS: 1598408-94-6
• 化学式: C₁₈H₂₂N₂O₂
• 分子量: 298.385
• InChiKey: ONKLNVKIMQDEKN-QZTJIDSGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  51
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (1R,2R)-N,N′-bis[(5-methylfuran-2-yl)methylidene]cyclohexane-1,2-diamine 在 sodium tetrahydroborate 作用下， 以 乙醇 为溶剂， 反应 1.0h， 以94%的产率得到(1R,2R)-N,N′-bis[(5-methylfuran-2-yl)methyl]cyclohexane-1,2-diamine
  参考文献：
  名称：

  Synthesis and fluorescent properties of novel chiral 1,2-diaminocyclohexane substituted ligands and their complexes

  摘要：

  A series of novel chiral 1,2-diaminocyclohexane derivatives bearing heterocyclic units were synthesized via improved methods under ultrasonic irradiation. The photophysical properties of compounds were studied in ethanol, methanol, and chloroform. The sensitivity of these amines toward Cu2+, Cd2+, and Ni2+ was studied by the UV vis and fluorescent methods. The pi-electron structure of thiophene and bithiophene containing sensors is the most active toward all above mentioned metal ions and is highly selective for Ni2+ and Cd2+. (c) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.02.092
• 作为产物：
  描述：

  5-甲基呋喃醛 、 trans-1,2-(R,R)-diammoniumcyclohexane tartrate 在 sodium hydroxide 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 72.0h， 以98%的产率得到(1R,2R)-N,N′-bis[(5-methylfuran-2-yl)methylidene]cyclohexane-1,2-diamine
  参考文献：
  名称：

  Synthesis and structural characterisation of copper complexes containing methylthiophene and methylfuryl derivatives of (R,R)-1,2-diaminocyclohexane as precatalysts for polymerisation of rac-lactide

  摘要：

  A series of Cu(II) complexes supported by methylthiophenyl-and methylfuryl-based (R,R)-1,2-diaminocyclohexane frameworks were synthesised. The synthesised complexes were characterised using infrared spectroscopy, elemental analysis, and single-crystal X-ray diffraction studies. The isopropoxide derivatives of the complexes were employed in the ring-opening polymerisation (ROP) of rac-lactide (rac-LA), yielding polylactides with high number-averaged molecular weight. The catalytic species in this study effectively mediated the stereoselective ROP of rac-LA in a physiological manner (P-r up to 0.92 at room temperature), with ROP activity being mainly dependent on steric hindrance and geometric constraints imposed by methyl substituents attached to the methylthiophenyl and methylfuryl ligands. (C) 2018 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2018.04.025