2-methyl-imidazo[1,2-c]pyrimidine | 33668-77-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2-methyl-imidazo[1,2-c]pyrimidine
• 英文别名: 2-Methylimidazo[1,2-c]pyrimidine
• CAS: 33668-77-8
• 化学式: C₇H₇N₃
• 分子量: 133.153
• InChiKey: IJSNEUNFZQDZTK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  30.2
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] IMIDAZO [1, 2-C] PYRIMIDIN-2-YLMETHYLPIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS<br/>[FR] IMIDAZO [1, 2-C] PYRIMIDIN-2-YLMÉTHYLPIPÉRIDINES COMME ANTAGONISTES VIS-À-VIS DES RÉCEPTEURS DE L'OREXINE
  申请人：GLAXO GROUP LTD

  公开号：WO2009003997A1

  公开（公告）日：2009-01-08

  This invention relates to imidazo[1,2-c]pyrimidin-2-ylmethyl substituted piperidine derivatives and their use as pharmaceuticals.

  这项发明涉及imidazo[1,2-c]嘧啶-2-基甲基取代的哌啶衍生物及其作为药物的应用。
• ORGANIC LIGHT EMITTING DEVICE
  申请人：Samsung Display Co., Ltd.

  公开号：US20170117478A1

  公开（公告）日：2017-04-27

  An organic light-emitting device having high efficiency and long lifespan including: a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode and including an emission layer, wherein the organic layer includes a first compound represented by Formula 1 and a second compound represented by Formula 2: When compounds represented by Formulae 1 and 2 are included in the emission layer, organic light-emitting devices may exhibit improved driving voltage, improved luminance, improved efficiency, and/or improved lifespans.

  一种具有高效率和长寿命的有机发光器件，包括：第一电极；面向第一电极的第二电极；以及位于第一电极和第二电极之间的有机层，包括一个发射层，其中该有机层包括由式1表示的第一化合物和由式2表示的第二化合物：当式1和式2表示的化合物包含在发射层中时，有机发光器件可能表现出改进的驱动电压、改进的亮度、改进的效率和/或改进的寿命。
• FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US20180116222A1

  公开（公告）日：2018-05-03

  The invention relates to novel compounds of the formula (I) in which R 1 , R 2 , R 3 , Q and n have the meanings given above, to their use as acaricides and/or insecticides for controlling animal pests and to processes and intermediates for their preparation.

  本发明涉及公式（I）的新化合物，其中R1，R2，R3，Q和n具有上述给定的含义，它们用作杀螨剂和/或杀虫剂以控制动物害虫，并提供它们的制备过程和中间体。
• IMIDAZO [1, 2-C] PYRIMIDIN-2-YLMETHYLPIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS
  申请人：Alvaro Giuseppe

  公开号：US20100210667A1

  公开（公告）日：2010-08-19

  Disclosed are imidazo[1,2-c]pyrimidin-2-ylmethyl substituted piperidine derivatives having the formula: where Ar is and where R 1 , R 2 , R 3 , n, p and q are as defined herein, and their use as pharmaceuticals.

  本发明涉及一种具有以下公式的咪唑[1,2-c]嘧啶-2-基甲基取代哌啶衍生物：其中Ar为，R1、R2、R3、n、p和q的定义如本文所述，并且它们作为药物的用途。
• Heteroaryl Amide Derivatives
  申请人：Hutchison Alan J.

  公开号：US20100216763A1

  公开（公告）日：2010-08-26

  Heteroaryl amide derivatives are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

  提供了杂环酰胺衍生物，其化学式为：其中变量如本文所述。这些化合物是配体，可用于体内或体外调节特定受体活性，并且在治疗与人类、家畜伴侣动物和家畜动物的病理性受体激活相关的疾病方面特别有用。提供了用于治疗此类疾病的制药组合物和方法，以及用于受体定位研究的此类配体的方法。