4,4-ethylenedioxy-3-phenylsulfonylcyclopentan-1-ol | 1040158-48-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4-ethylenedioxy-3-phenylsulfonylcyclopentan-1-ol
• 英文别名: 4,4-Ethylenedioxy-3-phenylsulfonylcyclopentan-1-ol；9-(benzenesulfonyl)-1,4-dioxaspiro[4.4]nonan-7-ol
• CAS: 1040158-48-2
• 化学式: C₁₃H₁₆O₅S
• 分子量: 284.333
• InChiKey: WLJPKWWSCGCLIK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  81.2
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2-chloro-4,4-ethylenedioxy-3-phenylsulfonylcyclopent-2-en-1-one 在 sodium tetrahydroborate 、 盐酸 作用下， 以 四氢呋喃 、 乙醇 为溶剂， 反应 4.0h， 以70%的产率得到4,4-ethylenedioxy-3-phenylsulfonylcyclopentan-1-ol
  参考文献：
  名称：

  Reactions of 2-Chloro-4,4-ethylenedioxy-3-phenylsulfonyl-cyclopent-2-en-1-one with some hydride reducing agents and carbon-centered nucleophiles

  摘要：

  2-Chloro-4,4-ethylenedioxy-3-phenylsulfonylcyclopent-2-en-1-one reacts with NaBH4 and LiAlH4 to give, depending on the conditions, 4,4-ethylenedioxy-2-chloro-3-phenylsulfonylcyclopent-2-en-1-ol and 4,4-ethylenedioxy-3-phenylsulfonylcyclopent-2-en-1-ol, as well as 4,4-ethylenedioxy-3-phenylsulfonylcyclopentan- 1-ol. Reactions of the title compound with diethyl malonate under basic conditions occurs at the double-bonded carbon atoms to form a couple of the addition-elimination products at C-2 and C-3.

  DOI：

  10.1134/s107042800709014x

文献信息

• Reactions of 2-Chloro-4,4-ethylenedioxy-3-phenylsulfonyl-cyclopent-2-en-1-one with some hydride reducing agents and carbon-centered nucleophiles
  作者：N. A. Ivanova、F. G. Usmanova、M. S. Miftakhov

  DOI：10.1134/s107042800709014x

  日期：2007.9

  2-Chloro-4,4-ethylenedioxy-3-phenylsulfonylcyclopent-2-en-1-one reacts with NaBH4 and LiAlH4 to give, depending on the conditions, 4,4-ethylenedioxy-2-chloro-3-phenylsulfonylcyclopent-2-en-1-ol and 4,4-ethylenedioxy-3-phenylsulfonylcyclopent-2-en-1-ol, as well as 4,4-ethylenedioxy-3-phenylsulfonylcyclopentan- 1-ol. Reactions of the title compound with diethyl malonate under basic conditions occurs at the double-bonded carbon atoms to form a couple of the addition-elimination products at C-2 and C-3.