| 1027098-09-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1027098-09-4
• 化学式: C₂HF₃O₂*C₁₃H₁₇N
• 分子量: 301.309
• InChiKey: HHOOCQBPKZVZFO-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 三氟过氧乙酸 、 sodium sulfite 作用下， 以 二氯甲烷 为溶剂， 生成 N-benzyl-3-methyl-3,4-epoxy-piperidine
  参考文献：
  名称：

  Synthesis of cis‐3‐methyl‐4‐aminopiperidine Derivatives

  摘要：

  A facile approach for the preparation of cis-3-methyl-4-aminopiperidine derivatives is described. The synthesis was carried out via regioselective ring opening of N-benzyl-3-methyl-3,4-epoxi-piperidine (8), which can be easily obtained in two steps from the corresponding N-benzyl-pyridinium salt (5). Seven new cis-3-methyl-4-amino and amido piperidines compounds were obtained.

  DOI：

  10.1080/00397910701865884