2-Cyclopentenyl 2,4-dichlorobenzoate | 122570-92-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Cyclopentenyl 2,4-dichlorobenzoate
• 英文别名: Cyclopent-2-en-1-yl 2,4-dichlorobenzoate
• CAS: 122570-92-7
• 化学式: C₁₂H₁₀Cl₂O₂
• 分子量: 257.116
• InChiKey: DPLSEMRJCXMIPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-Cyclopentenyl 2,4-dichlorobenzoate 、 膦酸,[[(二苯亚甲基)氨基]甲基]-,二(1,1-二甲基乙基)酯 在 palladium diacetate 、 三苯基膦 lithium hexamethyldisilazane 作用下， 生成 [(Benzhydrylidene-amino)-cyclopent-2-enyl-methyl]-phosphonic acid di-tert-butyl ester
  参考文献：
  名称：

  A practical synthesis of α-aminophosphonic acids.

  摘要：

  The preparation of diterbutyl-N (diphenylmethylene) aminomethylphosphonate 3 in four steps (42% overall yield) from N-hydroxymethyl phtalimide 1 is described. Various alpha-substituted alpha-aminophosphonic acids 5 containing functionalized unsaturated chains have been synthesized by alkylation of 3 under phase transfer catalysis with halides, Michael acceptors and palladium promoted reactions, followed by mild hydrolysis.

  DOI：

  10.1016/s0040-4039(00)77677-5

文献信息

• GENET, J. P.;UZIEL, J.;JUGE, S., TETRAHEDRON LETT., 29,(1988) N 36, C. 4559-4562
  作者：GENET, J. P.、UZIEL, J.、JUGE, S.

  DOI：——

  日期：——
• A practical synthesis of α-aminophosphonic acids.
  作者：J.P. Genêt、J. Uziel、M. Port、A.M. Touzin、S. Roland、S. Thorimbert、S. Tanier

  DOI：10.1016/s0040-4039(00)77677-5

  日期：1992.1

  The preparation of diterbutyl-N (diphenylmethylene) aminomethylphosphonate 3 in four steps (42% overall yield) from N-hydroxymethyl phtalimide 1 is described. Various alpha-substituted alpha-aminophosphonic acids 5 containing functionalized unsaturated chains have been synthesized by alkylation of 3 under phase transfer catalysis with halides, Michael acceptors and palladium promoted reactions, followed by mild hydrolysis.