1-methoxy-2,2,5,5-tetramethyl-4-phenyl-3-imidazoline | 88571-40-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-methoxy-2,2,5,5-tetramethyl-4-phenyl-3-imidazoline
• 英文别名: 1-Methoxy-2,2,5,5-tetramethyl-4-phenylimidazole
• CAS: 88571-40-8
• 化学式: C₁₄H₂₀N₂O
• 分子量: 232.326
• InChiKey: AWYDMFAWATXPHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  24.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,2,5,5-Tetramethyl-1-oxido-4-phenylimidazole 、 甲基肼 以29%的产率得到
  参考文献：
  名称：

  SHCHUKIN, G. I.;GRIGOREV, I. A.;VOLODARSKIJ, L. B., IZV. AN CCCP. CEP. XIM., 1983, N 10, 2357-2360

  摘要：

  DOI：

文献信息

• Convenient means of converting nitroxyl radicals into O-methylhydroxylamines
  作者：G. I. Shchukin、I. A. Grigor'ev、L. B. Volodarskii

  DOI：10.1007/bf00955785

  日期：1983.10
• Reactions of 3-imidazolines with diborane and sodium borohydride
  作者：V. A. Reznikov、L. B. Volodarskii

  DOI：10.1007/bf00963255

  日期：1985.10
• REZNIKOV, V. A.;VOLODARSKIJ, L. B., IZV. AN CCCP. CEP. XIM., 1985, N 10, 2337-2342
  作者：REZNIKOV, V. A.、VOLODARSKIJ, L. B.

  DOI：——

  日期：——
• Compounds for the treatment of pathologies associated with aging and degenerative disorders
  申请人：Niedernhofer Laura J.

  公开号：US20120004263A1

  公开（公告）日：2012-01-05

  The present invention relates to methods of inhibiting one or more signs of aging and/or degenerative disorder in a subject in need of such treatment, which comprise administering, to the subject, an effective amount of one or more of the compounds as set forth herein. “Inhibiting a sign of aging or degenerative disorder” means reducing the risk of occurrence, delaying the onset, slowing the progression, and/or reducing the severity and/or manifestation, of a sign of aging or degenerative disorder, and includes, but is not limited to, preventing the occurrence, development or progression of a sign of aging or degenerative disorder.
• SHCHUKIN, G. I.;GRIGOREV, I. A.;VOLODARSKIJ, L. B., IZV. AN CCCP. CEP. XIM., 1983, N 10, 2357-2360
  作者：SHCHUKIN, G. I.、GRIGOREV, I. A.、VOLODARSKIJ, L. B.

  DOI：——

  日期：——