Perfluorooctanoyl bromide | 222037-87-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: Perfluorooctanoyl bromide
• 英文别名: 2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluorooctanoyl bromide
• CAS: 222037-87-8
• 化学式: C₈BrF₁₅O
• 分子量: 476.96
• InChiKey: WQELDDKOSOQCBX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  16

文献信息

• Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
  申请人：Laboratory Skin Care, Inc.

  公开号：US10350168B2

  公开（公告）日：2019-07-16

  Dermal delivery compositions are provided. Aspects of the dermal delivery compositions include the presence of active agent-calcium phosphate particle complexes, where these complexes include uniform, rigid, spherical nanoporous calcium phosphate particles associated with one or more active agents. Also provided are methods of using the compositions in active agent delivery applications.

  提供了皮肤给药组合物。皮肤给药组合物的各个方面包括活性剂-磷酸钙颗粒复合物的存在，其中这些复合物包括与一种或多种活性剂相关联的均匀、硬质、球形纳米多孔磷酸钙颗粒。此外，还提供了在活性剂递送应用中使用这些组合物的方法。
• EP2337544A2
  申请人：——

  公开号：EP2337544A2

  公开（公告）日：2011-06-29
• DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME
  申请人：Laboratory Skin Care, Inc.

  公开号：EP2427178A2

  公开（公告）日：2012-03-14
• USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE
  申请人：Yu Betty

  公开号：US20090068255A1

  公开（公告）日：2009-03-12

  The application of matrix metalloproteinase (MMP) inhibitors to the skin inhibits the degradation of proteins found in the skin including collagen, elastin, and other basement membrane and extracellular matrix protein. MMP inhibitors may be used in both cosmetic compositions and pharmaceutical compositions for application to skin. MMP inhibitors are formulated with a cosmetically suitable vehicle or pharmaceutically acceptable excipient for application to the skin as creams, lotions, ointments, solutions, face masks, etc. As cosmetics, the inventive MMP inhibitor compositions are applied to the skin to prevent or reduce the appearance of wrinkles, pigmentation changes, loss of elasticity, or other effects associated with aging or sun damage. As pharmaceuticals, the inventive MMP inhibitor compositions may also be applied to the skin to treat or prevent a skin disease (e.g., proliferative disease, inflammatory disease).
• Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same
  申请人：Mansouri Zahra

  公开号：US20110189239A1

  公开（公告）日：2011-08-04

  Dermal delivery compositions are provided. Aspects of the dermal delivery compositions include the presence of active agent-calcium phosphate particle complexes, where these complexes include uniform, rigid, spherical nanoporous calcium phosphate particles associated with one or more active agents. Also provided are methods of using the compositions in active agent delivery applications.