Phthalic acid 1-((2S,3R,4S)-5-tert-butoxycarbonylamino-2,3,4-trimethoxy-pentyl) ester 2-pentachlorophenyl ester | 194663-63-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Phthalic acid 1-((2S,3R,4S)-5-tert-butoxycarbonylamino-2,3,4-trimethoxy-pentyl) ester 2-pentachlorophenyl ester
• CAS: 194663-63-3
• 化学式: C₂₇H₃₀Cl₅NO₉
• 分子量: 689.802
• InChiKey: DQQOOTTZDSVSHO-PONJGIIJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  42.0
• 可旋转键数：
  12.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  118.62
• 氢给体数：
  1.0
• 氢受体数：
  9.0

反应信息

• 作为反应物：
  描述：

  Phthalic acid 1-((2S,3R,4S)-5-tert-butoxycarbonylamino-2,3,4-trimethoxy-pentyl) ester 2-pentachlorophenyl ester 在 盐酸 作用下， 以 六甲基磷酰三胺 、 乙酸乙酯 为溶剂， 反应 244.0h， 生成 2,3,4-tri-O-methyl-1-deoxy-1-phthalimido-L-arabinitol
  参考文献：
  名称：

  Synthesis and condensation reactions of 1--O--5-O-[(]--

  摘要：

  1-Amino-l-deoxy-2,3,4-tri-O-methyl-5-O-[(pentachlorophenoxy)phthaloyl]-L-arabinitol hydrochloride was prepared from L-arabinose, and its inter-and intra-molecular condensation reactions were studied. In these reactions, a mixture of oligomers (in HMPA: 30%) besides the monomeric compound 2,3,4-tri-O-methyl-1-deoxy-1-phthalimido-L-arabinitol (in HMPA: 51%) were obtained. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0008-6215(97)00122-5
• 作为产物：
  描述：

  1-(tert-butoxycarbonylamino)-1-deoxy-2,3,4-tri-O-methyl-L-arabinitol 在 4-二甲氨基吡啶 、 N,N'-二环己基碳二亚胺 作用下， 以 吡啶 、 乙酸乙酯 为溶剂， 反应 96.0h， 生成 Phthalic acid 1-((2S,3R,4S)-5-tert-butoxycarbonylamino-2,3,4-trimethoxy-pentyl) ester 2-pentachlorophenyl ester
  参考文献：
  名称：

  Synthesis and condensation reactions of 1--O--5-O-[(]--

  摘要：

  1-Amino-l-deoxy-2,3,4-tri-O-methyl-5-O-[(pentachlorophenoxy)phthaloyl]-L-arabinitol hydrochloride was prepared from L-arabinose, and its inter-and intra-molecular condensation reactions were studied. In these reactions, a mixture of oligomers (in HMPA: 30%) besides the monomeric compound 2,3,4-tri-O-methyl-1-deoxy-1-phthalimido-L-arabinitol (in HMPA: 51%) were obtained. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0008-6215(97)00122-5