2-chloroacetanoylamino-6-lauroylaminopyridine | 412024-31-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-chloroacetanoylamino-6-lauroylaminopyridine
• 英文别名: N-[6-[(2-chloroacetyl)amino]pyridin-2-yl]dodecanamide
• CAS: 412024-31-8
• 化学式: C₁₉H₃₀ClN₃O₂
• 分子量: 367.919
• InChiKey: BFSSTAWENXRTPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  25
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  71.1
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-chloroacetanoylamino-6-lauroylaminopyridine 在 sodium azide 作用下， 以 乙醇 、 水 为溶剂， 反应 24.0h， 以94%的产率得到N-[6-[(2-叠氮乙酰基)氨基]吡啶-2-基]十二烷酰胺
  参考文献：
  名称：

  Self-Assembly and Characterization of Supramolecular [60]Fullerene-Containing 2,6-Diacylamidopyridine with Uracil Derivative by Hydrogen-Bonding Interaction

  摘要：

  [GRAPHICS]Novel self-assembly systems of uracil derivatives with organofullerene by a three-point hydrogen-bonding interaction were designed and established. The formation of hydrogen bonding was established by H-1 NMR studies in CDCl3.

  DOI：

  10.1021/ol025614i
• 作为产物：
  描述：

  月桂酰氯 以 四氢呋喃 为溶剂， 反应 42.0h， 生成 2-chloroacetanoylamino-6-lauroylaminopyridine
  参考文献：
  名称：

  Self-Assembly and Characterization of Supramolecular [60]Fullerene-Containing 2,6-Diacylamidopyridine with Uracil Derivative by Hydrogen-Bonding Interaction

  摘要：

  [GRAPHICS]Novel self-assembly systems of uracil derivatives with organofullerene by a three-point hydrogen-bonding interaction were designed and established. The formation of hydrogen bonding was established by H-1 NMR studies in CDCl3.

  DOI：

  10.1021/ol025614i

文献信息

• Self-Assembly and Characterization of Supramolecular [60]Fullerene-Containing 2,6-Diacylamidopyridine with Uracil Derivative by Hydrogen-Bonding Interaction
  作者：Zhiqiang Shi、Yuliang Li、Haofei Gong、Minghua Liu、Shengxiong Xiao、Huibiao Liu、Hongmei Li、Shengqiang Xiao、Daoben Zhu

  DOI：10.1021/ol025614i

  日期：2002.4.1

  [GRAPHICS]Novel self-assembly systems of uracil derivatives with organofullerene by a three-point hydrogen-bonding interaction were designed and established. The formation of hydrogen bonding was established by H-1 NMR studies in CDCl3.