4-(((6-chloro-3-pyridinyl)methyl)ethylamino)-2(5H)-oxazolone | 1203689-76-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-(((6-chloro-3-pyridinyl)methyl)ethylamino)-2(5H)-oxazolone
• 英文别名: 4-[(6-chloropyridin-3-yl)methyl-ethylamino]-5H-1,3-oxazol-2-one
• CAS: 1203689-76-2
• 化学式: C₁₁H₁₂ClN₃O₂
• 分子量: 253.688
• InChiKey: OSNASGFBZNDZTG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  54.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-氯-5-乙胺基甲基吡啶 、 4-methylsulfanyl-5H-oxazol-2-one 以 氯仿 为溶剂， 生成 4-(((6-chloro-3-pyridinyl)methyl)ethylamino)-2(5H)-oxazolone
  参考文献：
  名称：

  Discovery, synthesis, and evaluation of N-substituted amino-2(5H)-oxazolones as novel insecticides activating nicotinic acetylcholine receptors

  摘要：

  N-Substituted amino-2(5H)-oxazolones A are a novel class of insecticides acting as nicotinic acetylcholine receptor (nAChR) agonists and show potent activity against hemipteran insect species. Here we report the discovery and preparation of this class of chemistry. Our efforts in SAR elucidation, biological activity evaluation, as well as mode-of-action studies are also presented. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2014.03.037

文献信息

• N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：US20140315898A1

  公开（公告）日：2014-10-23

  The present invention relates to novel N-arylamide-substituted trifluoroethyl sulfide derivatives of the formula (I) in which X 1 , X 2 , X 3 , X 4 , R 1 , R 2 , R 3 , n have the meanings given in the description—to their use as acaricides and insecticides for controlling animal pests and to processes and intermediates for their preparation

  本发明涉及公式（I）中的新型N-芳酰胺取代三氟乙基硫醚衍生物，其中X1、X2、X3、X4、R1、R2、R3、n的含义如描述所示—它们作为杀螨剂和杀虫剂用于控制动物害虫，并涉及其制备的过程和中间体。
• ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US20160145235A1

  公开（公告）日：2016-05-26

  The present invention relates to aryl sulphide and aryl sulphoxide derivatives, to the use thereof as acaricides and insecticides for controlling animal pests and to processes and intermediates for preparation thereof. The aryl sulphide and aryl sulphoxide derivatives have the general structure (I) in which the respective radicals are as defined in the description.

  本发明涉及芳基硫醚和芳基亚砜衍生物，其用作杀螨剂和杀虫剂，用于控制动物害虫，并涉及其制备的过程和中间体。芳基硫醚和芳基亚砜衍生物具有一般结构（I），其中各自的基团如描述中所定义。
• HETEROCYCLIC COMPOUNDS AS PESTICIDES
  申请人：BAYER CROPSCIENCE AG

  公开号：US20150239847A1

  公开（公告）日：2015-08-27

  The present application relates to the use of heterocyclic compounds for controlling animal pests including arthropods, insects and nematodes, to novel heterocyclic compounds, to processes for their preparation and to intermediates for preparing the heterocyclic compounds.

  本申请涉及使用杂环化合物来控制动物害虫，包括节肢动物、昆虫和线虫，涉及新型杂环化合物，它们的制备方法以及制备杂环化合物的中间体。
• [EN] PESTICIDAL ARYLPYRROLIDINES<br/>[FR] ARYLPYRROLIDINES PESTICIDES
  申请人：BAYER IP GMBH

  公开号：WO2013135724A1

  公开（公告）日：2013-09-19

  Arylpyrrolidines of formula (I) wherein each substituent is as defined in the specification, and use thereof as pesticides and animal parasite-controlling agents.

  式(I)中的芳基吡咯烷，其中每个取代基如规范中定义的那样，并将其用作杀虫剂和动物寄生虫控制剂。
• Heterocyclic compounds as pesticides
  申请人：BRETSCHNEIDER Thomas

  公开号：US20120165345A1

  公开（公告）日：2012-06-28

  The present application relates to novel heterocyclic compounds, to the use thereof for controlling animal pests, which include arthropods and especially insects, and to processes for preparing the novel compounds.

  本申请涉及新型杂环化合物，其用于控制动物害虫，包括节肢动物，特别是昆虫，并涉及制备这些新化合物的方法。