1,2-epoxy-cyclohexane-1,2-dicarboxylic acid | 96096-74-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环己烷
• 英文名称: 1,2-epoxy-cyclohexane-1,2-dicarboxylic acid
• 英文别名: 1,2-Epoxy-cyclohexan-1,2-dicarbonsaeure；1,2-epoxycyclohexane-cis-1,2-dicarboxylic acid；Epoxycyclohexanedicarboxylic；7-oxabicyclo[4.1.0]heptane-1,6-dicarboxylic acid
• CAS: 96096-74-1
• 化学式: C₈H₁₀O₅
• 分子量: 186.164
• InChiKey: JDRLBWTVLBROJS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  87.1
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium hydroxide 作用下， 生成 1,2-epoxy-cyclohexane-1,2-dicarboxylic acid
  参考文献：
  名称：

  Recurrent gallstone ileus: a case report

  摘要：

  Gallstone ileus is a rare complication of recurrent gallstone cholecystitis and usually occurs in elderly female patients. Recurrent gallstone ileus occurs in 5% of patients with a previous episode of gallstone ileus and is associated with a mortality of 20%. We present a 52-year-old female with recurrent gallstone ileus 1 year after her initial episode.

  DOI：

  10.1007/s10140-002-0203-1

文献信息

• 7[(Carboxyoxiran-3-carboxamido)phenylacetamido]cephalosporin derivatives
  申请人：Pfizer Inc.

  公开号：US04064241A1

  公开（公告）日：1977-12-20

  A series of novel 7-(D-.alpha.-acylaminoarylacetamido)-.DELTA..sup.3 -cephem derivatives have been prepared wherein the acyl moiety contains an epoxy group immediately adjacent to the carbonyl carbon atom. These compounds are useful as antibacterial agents for the treatment of diseases caused by Gram-negative and Gram-positive bacteria. Preferred members include 7-[D-.alpha.-(cis-2-carboxyoxiran-3-carboxamido)phenylacetamido]-3-(1-meth yl-1,2,3,4-tetrazol-5-ylthiomethyl)-.DELTA..sup.3 -cephem-4-carboxylic acid and 7-[D.alpha.-(cis-2-carboxyoxiran-3-carboxamido)phenylacetamido]cephalospor anic acid. Alternate methods of preparation are provided for these compounds and the principal synthetic route is described in detail.

  一系列新型7-(D-.alpha.-酰胺基苯乙酰胺)-.DELTA..sup.3-头孢菌素衍生物已制备，其中酰基部分包含紧邻羰基碳原子的环氧基团。这些化合物可用作抗菌剂，用于治疗由革兰氏阴性和革兰氏阳性细菌引起的疾病。优选成员包括7-[D-.alpha.-(顺式-2-羧基氧环己烷-3-羧酰胺)苯乙酰胺]-3-(1-甲基-1,2,3,4-四唑-5-基硫甲基)-.DELTA..sup.3-头孢烯-4-羧酸和7-[D.alpha.-(顺式-2-羧基氧环己烷-3-羧酰胺)苯乙酰胺]头孢菌素酸。提供了这些化合物的替代制备方法，并详细描述了主要的合成路线。
• Synthetic resin composition having reduced corrosion-causing tendency and coloration
  申请人：Kyowa Chemical Industry Co., Ltd.

  公开号：EP0189899A2

  公开（公告）日：1986-08-06

  A synthetic resin composition having reduced corrosion-causing tendency and coloration, said composition comprising (A) 100 parts by weight of a synthetic resin containing halogen and/or an acidic substance, and (B) 0.001 to 50 parts by weight of a hydrotalcite solid solution represented by the following formula (1)wherein M2+1 represents at least one divalent metal cation, M2+2 represents at least one divalent metal cation, M3+ represents a trivalent metal cation, An- represents an anion having a valency of n, and x, yl, Y2 and m are positive numbers represented by the following expressions 0

  一种可降低腐蚀倾向和着色的合成树脂组合物，所述组合物包括：(A) 100 份（按重量计）含卤素和/或酸性物质的合成树脂，和(B) 0.001 至 50 份（按重量计）由下式（1）表示的氢滑石固溶体，其中 M2+1 代表至少一种二价金属阳离子，M2+2 代表至少一种二价金属阳离子，M3+ 代表一种三价金属阳离子，An- 代表一种化合价为 n 的阴离子，x、yl、Y2 和 m 为正数，用以下表达式表示 0树脂的腐蚀倾向或着色的方法。
• HYDROTALCITE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL FILM CONTAINING THE SAME
  申请人：Kyowa Chemical Industry Co., Ltd.

  公开号：EP1052223A1

  公开（公告）日：2000-11-15

  A hydrotalcite compound which has the excellent ability to absorb infrared rays and has excellent light transmission when contained in an agricultural film; a process for producing the compound; and an infrared absorber and an agricultural film both containing the compound. The hydrotalcite compound is characterized by retaining as the interlayer anions at least one kind of anions selected among ions of silicon-, phosphorus-, and boron-containing polymeric oxyacids and another kind of anions.

  一种水滑石化合物，它具有极佳的红外线吸收能力，并且在农膜中含有该化合物时具有极佳的透光性；一种生产该化合物的工艺；以及一种含有该化合物的红外线吸收剂和农膜。该氢铝酸盐化合物的特点是，作为层间阴离子，至少保留了一种从含硅、磷和硼的聚合氧酸离子中选出的阴离子和另一种阴离子。
• Bandseal for peg-filled hard capsule
  申请人：Qualicaps Co., Ltd.

  公开号：EP2402006A1

  公开（公告）日：2012-01-04

  The present invention provides a liquid for preparing a band seal for a hard capsule filled with a polyethylene glycol or a composition comprising a polyethylene glycol, the liquid is an aqueous solution containing a polyvinyl alcohol, polyvinyl alcohol copolymer or mixture thereof in a proportion to effect band sealing. The present invention further provides a process for preparing a filled hard capsule and a process for sealing a filled hard capsule.

  本发明提供了一种液体，用于制备填充有聚乙二醇或包含聚乙二醇的组合物的硬胶囊的带状密封，该液体是一种水溶液，含有聚乙烯醇、聚乙烯醇共聚物或其混合物，其比例可实现带状密封。本发明进一步提供了一种制备填充硬胶囊的工艺和一种密封填充硬胶囊的工艺。
• PHOTOCATIONIC CURABLE INKJET INK, PRODUCTION METHOD FOR PHOTOCATIONIC CURABLE INKJET INK, PRINTED ARTICLE, AND PRODUCTION METHOD FOR PRINTED ARTICLE
  申请人：Tokyo Printing Ink Mfg. Co. Ltd.

  公开号：EP3056551A1

  公开（公告）日：2016-08-17

  A photocationically curable ink jet ink includes: a photoacid generator; a pigment; a monofunctional epoxy compound; a bifunctional epoxy compound; a monofunctional oxetane compound; and a bifunctional oxetane compound. In the photocationically curable ink jet ink, a concentration of the monofunctional epoxy compound is 20 wt% to 50 wt%, a concentration of the bifunctional epoxy compound is 20 wt% to 50 wt%, a concentration of the monofunctional oxetane compound is 5 wt% to 20 wt%, and a concentration of the bifunctional oxetane compound is 5 wt% to 20 wt%.

  一种光致发光固化喷墨墨水包括：光酸发生器；颜料；单官能环氧化合物；双官能环氧化合物；单官能氧杂环丁烷化合物；以及双官能氧杂环丁烷化合物。在光致固化喷墨墨水中，单官能环氧化合物的浓度为 20 wt% 至 50 wt%，双官能环氧化合物的浓度为 20 wt% 至 50 wt%，单官能氧杂环丁烷化合物的浓度为 5 wt% 至 20 wt%，双官能氧杂环丁烷化合物的浓度为 5 wt% 至 20 wt%。