(+/-)-N-deacetylcolchicine | 102491-73-6
中文名称
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中文别名
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英文名称
(+/-)-N-deacetylcolchicine
英文别名
(+/-)-Desacetylcolchicin；7-amino-1,2,3,10-tetramethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one；Trimethylcolchicinic acid methyl ether
CAS
102491-73-6
化学式
C20H23NO5
mdl
——
分子量
357.406
InChiKey
HFPMXDMZJUJZBX-UHFFFAOYSA-N
BEILSTEIN
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EINECS
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
物化性质
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溶解度：溶于氯仿
计算性质
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辛醇/水分配系数(LogP)：0.9
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重原子数：26
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可旋转键数：4
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环数：3.0
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sp3杂化的碳原子比例：0.35
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拓扑面积：80
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氢给体数：1
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氢受体数：6
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 (R/S)-N-去乙酰基秋水仙裂碱 7-amino-10-hydroxy-1,2,3-trimethoxy-6,7-dihydro-5H-benzo[a]heptalen-9-one 68296-64-0 C19H21NO5 343.379 秋水仙碱 colchicine 64-86-8 C22H25NO6 399.444 N-(1,2,3,10-四甲氧基-9-氧代-5,6,7,9-四氢苯并[a]庚搭烯-7-基)乙酰胺 N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl) acetamide 54192-66-4 C22H25NO6 399.444 —— (+/-)-N-(trifluoroacetyl)deacetylcolchicine 102491-71-4 C22H22F3NO6 453.415 —— (+/-)-N-(trifluoroacetyl)deacetylcolchiceine 102491-70-3 C21H20F3NO6 439.388 —— (7RS)-7-hydroxy-1,2,3,10-tetramethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one 143731-66-2 C20H22O6 358.391 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 (7S)-7-氨基-1,2,3,10-四甲氧基-6,7-二氢-5H-苯并[g]庚搭烯-9-酮 deacetylcolchicine 3476-50-4 C20H23NO5 357.406 (+)-N-去乙酰基秋水仙碱 (+)-N-deacetylcolchicine 102419-91-0 C20H23NO5 357.406 秋水仙碱 colchicine 64-86-8 C22H25NO6 399.444 N-[(7R)-1,2,3,10-四甲氧基-9-氧代-6,7-二氢-5H-苯并[d]庚搭烯-7-基]乙酰胺 (+)-(as,7R)-colchicine 75520-89-7 C22H25NO6 399.444 N-(1,2,3,10-四甲氧基-9-氧代-5,6,7,9-四氢苯并[a]庚搭烯-7-基)乙酰胺 N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl) acetamide 54192-66-4 C22H25NO6 399.444 —— 1-benzyl-3-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-urea —— C28H30N2O6 490.556 —— (+/-)-N-butyryldeacetylcolchicine 102491-68-9 C24H29NO6 427.497 —— 3-(4-methoxy-phenyl)-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-propionamide —— C30H33NO7 519.595 —— 3-phenyl-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-propionamide —— C29H31NO6 489.568 N-[(S)-5,6,7,9-四氢-1,2,3,10-四甲氧基-9-氧代苯并[a]庚搭烯-7-基]-2,2,2-三氟乙酰胺 N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzoheptalen-7-yl)-(S)-2,2,2-trifluoroacetamide 26195-65-3 C22H22F3NO6 453.415 —— 2-phanyl-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide —— C28H29NO6 475.541 —— 2-(4-methoxy-phenyl)-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benxo[a]heptalen-7-yl)-acetamide —— C29H31NO7 505.568 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid benzyl ester —— C28H29NO7 491.541 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 4-methyl benzyl ester —— C29H31NO7 505.568 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 4-methoxy benzyl ester —— C29H31NO8 521.567 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptaen-7-yl)-carbamic acid cyclopentyl methyl ester —— C27H33NO7 483.562 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 4-isopropyl benzyl ester —— C31H35NO7 533.621 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid cyclohexylmethyl esterr —— C28H35NO7 497.588 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 4-bromo benzyl ester —— C28H28BrNO7 570.437 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 4-fluoro benzyl ester —— C28H28FNO7 509.531 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 3-fluoro benzyl ester —— C28H28FNO7 509.531 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 2-fluoro benzyl ester —— C28H28FNO7 509.531 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 4-nitro benzyl ester —— C28H28N2O9 536.538 —— 2-(9H-fluoren-9-yl)-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-acetamide —— C35H33NO6 563.65 —— 3-(9H-fluoren-9-yl)-N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-propionamide —— C36H35NO6 577.677 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid indan-1-ylmethyl ester —— C31H33NO7 531.606 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 2-(9H-fluoren-9-yl)-ethyl ester —— C36H35NO7 593.676 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester —— C35H33NO7 579.65 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 1,2,3,4-tetrahydro-naphthalen-1-ylmethyl ester —— C32H35NO7 545.632 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 2,7-di-tert-butyl-9H-fluoren-9-ylmethyl ester —— C43H49NO7 691.865 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 2-bromo-9H-fluoren-9-ylmethyl ester —— C35H32BrNO7 658.546 —— (1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-carbamic acid 1-methyl-9H-fluoren-9-ylmethyl ester —— C36H35NO7 593.676 - 1
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反应信息
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作为反应物：描述：(+/-)-N-deacetylcolchicine 在 碳酸氢钠 作用下，