methyl 4-hydroxy-3-(2',3'-dihydroxy-3'-methylbutyl)benzoate | 117176-70-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: methyl 4-hydroxy-3-(2',3'-dihydroxy-3'-methylbutyl)benzoate
• 英文别名: methyl 3-(2,3-dihydroxy-3-methylbutyl)-4-hydroxybenzoate；hostmaniane
• CAS: 117176-70-2
• 化学式: C₁₃H₁₈O₅
• 分子量: 254.283
• InChiKey: ABFHVQPVDSMGNR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  甲基4-羟基-3-(3-甲基丁-2-烯基)苯甲酸酯 在 四氧化锇 、 N-甲基吗啉氧化物 作用下， 以 水 、 丙酮 、 叔丁醇 为溶剂， 反应 12.0h， 以92%的产率得到methyl 4-hydroxy-3-(2',3'-dihydroxy-3'-methylbutyl)benzoate
  参考文献：
  名称：

  基于 13C NMR 化学位移诊断规则的四类异戊二烯化芳香族天然产物的结构修正

  摘要：

  在阐明具有 2,3-环氧、2,3-二羟基的四类天然异戊二烯化芳族化合物的结构以及与邻苯酚羟基环化以产生吡喃或呋喃环部分的结构时，经常会出现错误并且不可避免。在严谨的文献研究和一系列化学转化实验的基础上，制定了基于13 C NMR 数据快速测定这四类异戊二烯化衍生物的规则，并据此报告了这些片段的 57 次修正。

  DOI：

  10.1021/acs.joc.0c02409

文献信息

• Herbal compositions and methods for the prevention and treatment of plant of nail infections
  申请人：MONDIAS NATURELS INC.

  公开号：US10792322B2

  公开（公告）日：2020-10-06

  It is disclosed a pharmaceutical and/or phytosanitary composition comprising an aqueous extract of Chelidonium majus root and an acceptable pharmaceutical or phytosanitary excipient, for the prevention or treatment of plant infections and/or for the prevention or treatment of nail 5 infections. The composition may further comprise an aqueous extract of Thuja occidentalis leaf; and from about 1 to 5% of at least one natural phenolic compound. The composition is efficient in the treatment of plant infection (mildew fungus, blight fungus, etc); the treatment of intumescence of a plant; the treatment of potatoes (powdery or common scab, Rhizoctonia, etc), and also allows a higher crop yield: without the use of a chemical fungicide. The composition also allows rapid treatment of fungus infection of nails.

  本发明公开了一种药物和/或植物检疫组合物，该组合物包含一种Chelidonium majus根的水提取物和一种可接受的药物或植物检疫赋形剂，用于预防或治疗植物感染和/或预防或治疗指甲5感染。该组合物还可进一步包含Thuja occidentalis叶的水提取物；以及约1%至5%的至少一种天然酚类化合物。该组合物能有效治疗植物感染（霜霉病菌、枯萎病菌等）；治疗植物溃烂；治疗马铃薯（白粉病或普通疮痂病、根瘤菌等），还能在不使用化学杀菌剂的情况下提高作物产量。该成分还能快速治疗指甲的真菌感染。
• HERBAL COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF PLANT OR NAIL INFECTIONS
  申请人：Mondias Naturels Inc.

  公开号：EP3413904A1

  公开（公告）日：2018-12-19
• Herbal Compositions and Methods for the Prevention and Treatment of Plant of Nail Infections
  申请人：MONDIAS NATURELS INC.

  公开号：US20190038696A1

  公开（公告）日：2019-02-07

  It is disclosed a pharmaceutical and/or phytosanitary composition comprising an aqueous extract of Chelidonium majus root and an acceptable pharmaceutical or phytosanitary excipient, for the prevention or treatment of plant infections and/or for the prevention or treatment of nail 5 infections. The composition may further comprise an aqueous extract of Thuja occidentalis leaf; and from about 1 to 5% of at least one natural phenolic compound. The composition is efficient in the treatment of plant infection (mildew fungus, blight fungus, etc); the treatment of intumescence of a plant; the treatment of potatoes (powdery or common scab, Rhizoctonia etc), and also allows a higher crop yield: without the use of a chemical fungicide. The composition also allows rapid treatment of fungus infection of nails.
• Herbal Compositions and Methods for the Prevention and Treatment of Nail Infections
  申请人：Produits Naturels Mondias Inc.

  公开号：US20210069277A1

  公开（公告）日：2021-03-11

  It is disclosed a pharmaceutical and/or phytosanitary composition comprising an aqueous extract of Chelidonium majus root and an acceptable pharmaceutical or phytosanitary excipient for the prevention or treatment of nail infections. The composition may further comprise an aqueous extract of Thuja occidentalis leaf; and from about 1 to 5% of at least one natural phenolic compound. The composition is efficient in the treatment of plant infection (mildew fungus, blight fungus, etc); the treatment of intumescence of a plant; the treatment of potatoes (powdery or common scab, Rhizoctonia, etc), and also allows a higher crop yield: without the use of a chemical fungicide. The composition also allows rapid treatment of fungus infection of nails.
• [EN] HERBAL COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF PLANT OR NAIL INFECTIONS<br/>[FR] COMPOSITIONS À BASE DE PLANTES ET PROCÉDÉS DE PRÉVENTION ET DE TRAITEMENT D'INFECTIONS DE PLANTES OU D'INFECTIONS UNGUÉALES
  申请人：MONDIAS NATURELS INC

  公开号：WO2017136930A1

  公开（公告）日：2017-08-17

  It is disclosed a pharmaceutical and/or phytosanitary composition comprising an aqueous extract of Chelidonium majus root and an acceptable pharmaceutical or phytosanitary excipient, for the prevention or treatment of plant infections and/or for the prevention or treatment of nail 5 infections. The composition may further comprise an aqueous extract of Thuja occidentalis leaf; and from about 1 to 5% of at least one natural phenolic compound. The composition is efficient in the treatment of plant infection (mildew fungus, blight fungus, etc); the treatment of intumescence of a plant; the treatment of potatoes (powdery or common scab, Rhizoctonia, etc), and also allows a higher crop yield: without the use of a chemical fungicide. The composition also allows rapid treatment of fungus infection of nails.