5,10,15,20-四(2-噻吩基)卟啉 | 22112-87-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 中文名称: 5,10,15,20-四(2-噻吩基)卟啉
• 英文名称: 5,10,15,20-Tetra-2-thienyl-Porphine
• 英文别名: 5,10,15,20-tetrathiophen-2-yl-21,23-dihydroporphyrin
• CAS: 22112-87-4
• 化学式: C₃₆H₂₂N₄S₄
• 分子量: 638.9
• InChiKey: QTBZIEZZDWDDFD-UHFFFAOYSA-N

物化性质

• 熔点：
  >300 °C
• 密度：
  1.424±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  9.3
• 重原子数：
  44
• 可旋转键数：
  4
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  170
• 氢给体数：
  2
• 氢受体数：
  6

安全信息

• 海关编码：
  2934999090

文献信息

• Electrode for active oxygen species and sensor using the electrode
  申请人：Yuasa Makoto

  公开号：US20050077192A1

  公开（公告）日：2005-04-14

  An electrode for active oxygen species comprising a conductive component with a polymer membrane of a metal porphyrin complex formed on the surface is disclosed. The electrode for active oxygen species can detect active oxygen species such as superoxide anion radicals, hydrogen peroxide, and .OH and other active radical species (NO, ONOO—, etc.) in any environment including in vivo environment as well as in vitro environment. The electrode thus can be used for specifying various diseases and examining active oxygen species in food or in water such as tap water and sewage water.

  本发明公开了一种活性氧物种电极，其包括一个导电组件和形成在其表面上的金属卟啉复合物聚合物膜。该活性氧物种电极可以检测任何环境中的活性氧物种，包括体内环境和体外环境中的超氧阴离子自由基、过氧化氢和.OH等活性自由基物种（NO、ONOO-等）。因此，该电极可用于指定各种疾病，并检查食品或水中的活性氧物种，如自来水和污水。
• ELECTRODE FOR ACTIVE OXYGEN SPECIES AND SENSOR USING THE ELECTRODE
  申请人：YUASA Makoto

  公开号：US20110315551A1

  公开（公告）日：2011-12-29

  An electrode for active oxygen species comprising a conductive component with a polymer membrane of a metal porphyrin complex formed on the surface is disclosed. The electrode for active oxygen species can detect active oxygen species such as superoxide anion radicals, hydrogen peroxide, and .OH and other active radical species (NO, ONOO—, etc.) in any environment including in vivo environment as well as in vitro environment. The electrode thus can be used for specifying various diseases and examining active oxygen species in food or in water such as tap water and sewage water.

  公开了一种用于活性氧物种的电极，其中包括一个导电组分和在其表面形成的金属卟啉复合物的聚合物膜。该电极可以检测任何环境中的活性氧物种，包括体内环境和体外环境中的超氧阴离子自由基、过氧化氢、.OH和其他活性自由基物种（NO、ONOO—等）。因此，该电极可用于指定各种疾病并检查食品或水中的活性氧物种，例如自来水和污水。
• ACTIVE OXYGEN SPECIES MEASURING DEVICE
  申请人：Yuasa, Makoto

  公开号：EP1600766A1

  公开（公告）日：2005-11-30

  A reactive oxygen species measuring device according to the present invention comprises a reactive oxygen species sensor provided with an electrode assembly capable of detecting the presence of reactive oxygen species or the like in terms of an electric current, a power source means for applying a measuring voltage to the reactive oxygen species sensor, and a reactive oxygen species concentration measuring means for measuring a concentration of the reactive oxygen species or the like from the current detected by the reactive oxygen species sensor. According to the present invention, a concentration of reactive oxygen species or the like such as in vivo or in vitro superoxide anion radical (O2-.) can be measured reliably, and the entire device can be formed in a smaller size and always mounted to a living body. In addition, the measured data can be transmitted to a remote place or location, and further, the health condition of a living body or the like determined in the remote place can be returned to a measuring place and informed, and thus, the health condition of the living body can be monitored by measuring and monitoring reactive oxygen species.

  根据本发明，一种活性氧测量装置包括一个活性氧传感器，其电极组件能够以电流形式检测活性氧或类似物的存在；一个电源装置，用于向活性氧传感器施加测量电压；以及一个活性氧浓度测量装置，用于根据活性氧传感器检测到的电流测量活性氧或类似物的浓度。根据本发明，可以可靠地测量体内或体外超氧阴离子自由基（O2-.）等活性氧或类似物的浓度，而且整个装置可以形成较小的尺寸，并始终安装在活体上。此外，还可将测量数据传输到远程地点或位置，并进一步将远程地点确定的活体或类似物的健康状况返回到测量地点并告知，因此可通过测量和监测活性氧来监测活体的健康状况。
• ELECTRODE FOR SUPEROXIDE ANION AND SENSOR INCLUDING THE SAME
  申请人：Yuasa, Makoto

  公开号：EP1731902A1

  公开（公告）日：2006-12-13

  An electrode for superoxide anions characterized by comprising a conductive component and, superimposed on a surface thereof, a film resulting from electrolytic polymerization of a metal thiofurylporphyrin/axial ligand complex; and a sensor for measuring a superoxide anion concentration including the same. The electrode for superoxide anions, by virtue of not only the excellent performance of electrode provided with the metal porphyrin complex polymer film, but also the presence of the axial ligand, can prevent poisoning by a catalyst poison such as hydrogen peroxide. Accordingly, in any of in vitro or in vivo environments, this electrode for superoxide anions enables detection of superoxide anion radicals without suffering any influence from a catalyst poison such as hydrogen peroxide. Moreover, quantitative assay of superoxide anions can be performed by the use of this electrode for superoxide anion in combination with a counter electrode or a reference electrode. Thus, this electrode for superoxide anions can find wide applicability in various fields.

  一种超氧阴离子电极，其特征在于包括导电部件和叠加在其表面上的由金属硫卟啉/轴向配体络合物电解聚合而成的薄膜；以及包括该部件的测量超氧阴离子浓度的传感器。这种超氧阴离子电极不仅具有金属卟啉络合物聚合物薄膜电极的优异性能，而且由于轴配体的存在，可以防止过氧化氢等催化剂毒物的中毒。因此，在任何体外或体内环境中，这种超氧阴离子电极都能检测超氧阴离子自由基，而不会受到过氧化氢等催化剂毒物的影响。此外，这种超氧阴离子电极还可与反电极或参比电极结合使用，对超氧阴离子进行定量检测。因此，这种超氧阴离子电极可广泛应用于各个领域。
• Reactive oxygen species measuring device
  申请人：Yuasa Makoto

  公开号：US20060289313A1

  公开（公告）日：2006-12-28

  A reactive oxygen species measuring device according to the present invention comprises a reactive oxygen species sensor provided with an electrode assembly capable of detecting the presence of reactive oxygen species or the like in terms of an electric current, a power source means for applying a measuring voltage to the reactive oxygen species sensor, and a reactive oxygen species concentration measuring means for measuring a concentration of the reactive oxygen species or the like from the current detected by the reactive oxygen species sensor. According to the present invention, a concentration of reactive oxygen species or the like such as in vivo or in vitro superoxide anion radical (O 2 − .) can be measured reliably, and the entire device can be formed in a smaller size and always mounted to a living body. In addition, the measured data can be transmitted to a remote place or location, and further, the health condition of a living body or the like determined in the remote place can be returned to a measuring place and informed, and thus, the health condition of the living body can be monitored by measuring and monitoring reactive oxygen species.