(2-Hexadecanoyloxy-3-hydroxypropyl) octadec-9-enoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: (2-Hexadecanoyloxy-3-hydroxypropyl) octadec-9-enoate
• 化学式: C₃₇H₇₀O₅
• 分子量: 594.9
• InChiKey: DOZKMFVMCATMEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.2
• 重原子数：
  42
• 可旋转键数：
  35
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Pharmaceutical compositions having a modified vehicle
  申请人：——

  公开号：US20040170650A1

  公开（公告）日：2004-09-02

  A composition comprising: (a) one to three bioactive agents; and (b) a vehicle comprising; (i) a modified liquid carrier, and (ii) an unmodified liquid carrier wherein the ratio by volume of the modified liquid carrier to the unmodified liquid carrier is between 0.00001:99.99999 to less than 0.01:99.99, that provide the composition with predictable sustained-release properties and wherein immediately after manufacture of the composition, said composition can be administered to a host such that the one to three bioactive agents is released to the host on a sustained basis.

  一种组合物，包括 (a) 一至三种生物活性剂；和 (b) 一种载体，包括 (i) 改性液体载体，和 (ii) 未改性液体载体 其中，改性液体载体与未改性液体载体的体积比介于 0.00001:99.99999 至小于 0.01:99.99 之间，从而使该组合物具有可预测的持续释放特性，并且在制造该组合物后，可立即将所述组合物施用到宿主体内，从而使一至三种生物活性剂持续释放到宿主体内。
• USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES
  申请人：TRUSTEES OF BOSTON UNIVERSITY

  公开号：EP0655907B1

  公开（公告）日：1999-04-28
• PROCESS FOR THE PRODCUTION OF GLYCERIDES WITH LIPASES
  申请人：NIPPON SUISAN KAISHA, LTD.

  公开号：EP1300470B1

  公开（公告）日：2010-09-15
• PHARMACEUTICAL COMPOSITIONS HAVING A MODIFIED VEHICLE
  申请人：Zoetis Services LLC

  公开号：EP1569693B1

  公开（公告）日：2016-12-28
• Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition
  申请人：——

  公开号：US20040115822A1

  公开（公告）日：2004-06-17

  The present invention provides a method of characterizing the transfer of an analyte from a non-aqueous liquid composition to an aqueous medium and in particular to an in vitro method for measuring the dissolution of a drug from a sustained release dosage form.