3,3'-Dihydroxy-5-methoxy-2,5',6-tris-(p-hydroxybenzyl)bibenzyl

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 3,3'-Dihydroxy-5-methoxy-2,5',6-tris-(p-hydroxybenzyl)bibenzyl
• 英文别名: 3-[2-[3-hydroxy-5-[(4-hydroxyphenyl)methyl]phenyl]ethyl]-2,4-bis[(4-hydroxyphenyl)methyl]-5-methoxyphenol
• 化学式: C₃₆H₃₄O₆
• 分子量: 562.6
• InChiKey: GHCPQTZTSCKOLR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  42
• 可旋转键数：
  10
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  110
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• Adhesive including medicament
  申请人：LOMA LINDA UNIVERSITY MEDICAL CENTER

  公开号：EP1803473A2

  公开（公告）日：2007-07-04

  The present invention provides medicament-containing cyanoacrylate adhesive formulations for sealing wounds. The adhesive comprises a cyanoacrylate, a substance, and a defect forming agent, wherein the defect forming agent is capable of being removed from a cured cyanoacrylate matrix by solvation in an aqueous solution whereby a plurality of defects in the matrix are formed permitting release of the substance from the matrix at a controlled rate.

  本发明提供了用于密封伤口的含药物的氰基丙烯酸酯粘合剂配方。该粘合剂包括一种氰基丙烯酸酯、一种物质和一种缺陷形成剂，其中缺陷形成剂能够通过在水溶液中的溶解从固化的氰基丙烯酸酯基质中去除，从而在基质中形成多个缺陷，使物质能够以可控的速率从基质中释放出来。
• Deployable multifunctional hemostatic agent
  申请人：Zhu Hua Yong

  公开号：US20050123588A1

  公开（公告）日：2005-06-09

  This invention relates to deployable hemostatic materials comprising chitosan fibers upon which hemostatic microporous polysaccharide microspheres and a medicament or biologically active substance are deposited. The hemostatic materials are suitable for use in controlling active bleeding from artery and vein lacerations, sealing femoral artery punctures, and controlling oozing from tissue.

  本发明涉及由壳聚糖纤维组成的可展开止血材料，壳聚糖纤维上沉积有止血微孔多糖微球和药物或生物活性物质。这种止血材料适用于控制动脉和静脉裂口的活动性出血、封闭股动脉穿刺口以及控制组织渗出。
• ADHESIVE INCLUDING MEDICAMENT
  申请人：Loma Linda University Medical Center

  公开号：EP1409033A1

  公开（公告）日：2004-04-21
• EP1638491A4
  申请人：——

  公开号：EP1638491A4

  公开（公告）日：2008-05-28
• DEPLOYABLE MULTIFUNCTIONAL HEMOSTATIC AGENT
  申请人：LOMA LINDA UNIVERSITY MEDICAL CENTER

  公开号：EP1638491A2

  公开（公告）日：2006-03-29