2-Propenyl 2-propenethiosulfonate

• 分子结构分类: 有机化合物 - 有机硫化合物 - 烯丙基硫化合物
• 英文名称: 2-Propenyl 2-propenethiosulfonate
• 英文别名: oxo-prop-2-enoxy-prop-2-enyl-sulfanylidene-λ6-sulfane
• 化学式: C₆H₁₀O₂S₂
• 分子量: 178.3
• InChiKey: GNZRFGFYMUUFRF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  66.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Antimicrobial blood treatment using allicin and related compounds
  申请人：——

  公开号：US20030077264A1

  公开（公告）日：2003-04-24

  Methods and compositions prolonging the storage life and/or increasing the safety of a blood product, such as whole blood, red blood cells, white blood cells, platelets, serum and aqueous additive solutions for storage of such blood products are provided. Storage solutions of this invention comprise a composition selected from the group consisting of garlic extract, allicin, other microorganism-growth-inhibiting compounds derived from garlic, and analogs and derivatives of allicin and said other compounds, in an amount effective to inhibit growth of at least one selected microorganism which is a bacterium, virus, fungus or parasite. The storage additive solutions of this invention can increase platelet storage life by at least about 20%, preferably at least about 40%.

  本发明提供了一种延长血液制品（如全血、红细胞、白细胞、血小板、血清和用于储存这种血液制品的水性添加剂溶液）的储存寿命和/或提高安全性的方法和组合物。本发明的储存溶液包括从大蒜提取的化合物、大蒜素、从大蒜中提取的其他微生物生长抑制化合物以及大蒜素和该等化合物的类似物和衍生物中选择的一种组成，其有效抑制至少一种选择的细菌、病毒、真菌或寄生虫的生长。本发明的储存添加剂溶液可以将血小板的储存寿命延长至少20％，最好至少40％。
• [EN] LOCAL DRUG DELIVERY SYSTEM IN CORONARY STENTS<br/>[FR] SYSTEME D'ADMINISTRATION LOCALE DE MEDICAMENT DANS DES EXTENSEURS CORONAIRES
  申请人：SAHAJANAND BIOTECH PRIVATE LTD

  公开号：WO2003018080A1

  公开（公告）日：2003-03-06

  The invention provides an implantable medical device comprising a substrate and a biocompatible polymeric coating which covers at least a portion of the said substrate, and wherein the coating contains ajoene and/or allicin or isomers, analogues, homologues or derivatives thereof, a composition comprising biocompatible polymer/s and ajoene and/or allicin suitable for use in coating the implantable medical device.
• [EN] LOCAL DRUG DELIVERY SYSTEM IN CORONARY STENTS<br/>[FR] SYSTEME D'ADMINISTRATION LOCALE DE MEDICAMENT DANS DES ENDOPROTHESES CORONAIRES
  申请人：SAHAJANAND BIOTECH PRIVATE LTD

  公开号：WO2003018082A2

  公开（公告）日：2003-03-06

  The invention provides an implantable medical device comprising a substrate and a biocompatible polymeric coating which covers at least a portion of the said substrate, and wherein the coating contains ajoene and/or allicin or isomers, analogues, homologues or derivatives thereof, a composition comprising biocompatible polymer/s and ajoene and/or allicin suitable for use in coating the implantable medical device.