2,9-diaminodecanedioic acid | 91346-99-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,9-diaminodecanedioic acid
• 英文别名: 2,9-diamino-sebacinic acid；2,9-diamino-decanedioic acid；2,9-Diamino-decandisaeure；2.9-Diamino-sebacinsaeure；α.λ-Diamino-octan-α.λ-dicarbonsaeure；α.α'-Diamino-sebacinsaeure；2,9-Diammoniodecanedioate；2,9-bis(azaniumyl)decanedioate
• CAS: 91346-99-5
• 化学式: C₁₀H₂₀N₂O₄
• mdl: MFCD00545085
• 分子量: 232.28
• InChiKey: JOOVPMLVPBHUEJ-UHFFFAOYSA-N

物化性质

• 熔点：
  >360 °C
• 沸点：
  447.2±45.0 °C(Predicted)
• 密度：
  1.216±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -4.4
• 重原子数：
  16
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  127
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2,9-diaminodecanedioic acid 在 盐酸 、 氨 作用下， 生成 2,9-diureido-decanedioic acid dimethyl ester
  参考文献：
  名称：

  Notes - Improved Procedure for Preparing 3-,5-, or 3,5-Substituted Hydantoins

  摘要：

  DOI：

  10.1021/jo01355a602
• 作为产物：
  描述：

  α,α'-dibromosebacate de dimethyle 在 盐酸 、 tin 、 sodium nitrite 作用下， 生成 2,9-diaminodecanedioic acid
  参考文献：
  名称：

  The irradiation history of the Ghubara (L5) regolith breccia

  摘要：

  Abstract— We measured cosmic‐ray products—noble gases, radionuclides, thermoluminescence, and nuclear tracks—and trace element contents and mineralogy of samples of three orthogonal and mutually intersecting cores (41–46 cm long) of a 101.6 kg Ghubara individual (1958,805) at The Natural History Museum, London. The xenoliths, like the host, have high concentrations of trapped solar gases and are heavily shocked. While contents of noble gases and degree of shock‐loading in this individual and three others differ somewhat, the data indicate that Ghubara is a two‐generation regolith breccia. Contents of cosmogenic 26Al and 10Be and low track densities indicate that the Ghubara individuals were located more than 15 cm below the surface of an 85 cm meteoroid. Because of its large size, Ghubara's cosmic‐ray exposure age is poorly defined to be 15–20 Ma from cosmogenic nuclides. Ghubara's terrestrial age, based on 14C data, is 2–3 ka. Not only is Ghubara the first known case of a two‐generation regolith breccia on the macroscale, it also has a complicated thermal and irradiation history.

  DOI：

  10.1111/j.1945-5100.2002.tb00819.x

文献信息

• Method for preparing a ligand presenting assembly (LPA), an LPA and uses thereof
  申请人：Statens Serum Institut

  公开号：US20040086949A1

  公开（公告）日：2004-05-06

  The present invention relates to a method for preparing a ligand presenting assembly (LPA), an LPA, an immunological composition and a vaccine. The invention further relates to a method for generating antibodies, a kit for use in diagnosis and use of an LPA for preparing a pharmaceutical composition.

  本发明涉及一种制备配体呈现组装体（LPA）、LPA、免疫组合物和疫苗的方法。该发明还涉及一种产生抗体的方法，用于诊断的试剂盒以及使用LPA制备药物组合物的方法。
• Acetylen-Aminos�uren
  作者：K. Schl�gl

  DOI：10.1007/bf00898759

  日期：——
• Neuberg; Neimann, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1905, vol. 45, p. 120
  作者：Neuberg、Neimann

  DOI：——

  日期：——
• US2109929
  申请人：——

  公开号：——

  公开（公告）日：——
• LIGAND PRESENTING ASSEMBLY (LPA), METHOD OF PREPARATION AND USES THEREOF
  申请人：Statens Serum Institut

  公开号：EP1117677B1

  公开（公告）日：2003-11-12