10-(2-hydroxyethyl)-9-methyl-2,3,6,7-tetrahydro-1H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11(5H)-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 10-(2-hydroxyethyl)-9-methyl-2,3,6,7-tetrahydro-1H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11(5H)-one
• 英文别名: 5-(2-hydroxyethyl)-6-methyl-3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(17),2(7),5,8-tetraen-4-one
• 化学式: C₁₈H₂₁NO₃
• 分子量: 299.4
• InChiKey: JQTCRWPNGSAKNE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Coumarin-based compounds and related methods
  申请人：Biosearch Technologies, Inc.

  公开号：US11034677B2

  公开（公告）日：2021-06-15

  The present invention generally relates to coumarin-based compounds that can be used for the labeling of biological molecules, as well as related synthetic and testing methods. The coumarin-based compounds typically survive conditions necessary for automated synthesis of nucleic acids without undergoing any substantial degree of degradation or alteration.

  本发明一般涉及可用于标记生物分子的香豆素基化合物以及相关的合成和测试方法。香豆素基化合物通常能在核酸自动合成所需的条件下存活，而不会发生任何程度的降解或改变。
• [EN] COUMARIN-BASED COMPOUNDS AND RELATED METHODS<br/>[FR] COMPOSÉS À BASE DE COUMARINE ET PROCÉDÉS ASSOCIÉS
  申请人：BIOSEARCH TECHNOLOGIES INC

  公开号：WO2016118305A1

  公开（公告）日：2016-07-28

  The present invention generally relates to coumarin-based compounds that can be used for the labeling of biological molecules, as well as related synthetic and testing methods. The coumarin-based compounds typically survive conditions necessary for automated synthesis of nucleic acids without undergoing any substantial degree of degradation or alteration.