1-myristoyloxy-2,3-bis-palmitoyloxy-propane | 60138-14-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 1-myristoyloxy-2,3-bis-palmitoyloxy-propane
• 英文别名: 1-Myristoyloxy-2,3-bis-palmitoyloxy-propan；1,2-Dipalmitoyl-3-myristoyl-rac-glycerol；(2-hexadecanoyloxy-3-tetradecanoyloxypropyl) hexadecanoate
• CAS: 60138-14-9
• 化学式: C₄₉H₉₄O₆
• 分子量: 779.282
• InChiKey: JWVXCFSNEOMSHH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  20.9
• 重原子数：
  55
• 可旋转键数：
  48
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  棕榈酰氯 、 alkaline earth salt of/the/ methylsulfuric acid 在 吡啶 、 苯 作用下， 生成 1-myristoyloxy-2,3-bis-palmitoyloxy-propane
  参考文献：
  名称：

  Carter; Malkin, Journal of the Chemical Society, 1939, p. 578

  摘要：

  DOI：

文献信息

• Lipids for modulating immune response
  申请人：——

  公开号：US20040023922A1

  公开（公告）日：2004-02-05

  A product and the use thereof to stimulate and/or modulate immune response in animals and humans, comprising lipids having a glycerol backbone carrying at least one alkyl or acyl chain, wherein the lipid is phospholipid, glycolipid or neutral lipid, saturated or unsaturated, and the number of carbon atoms in the hydrocarbon tails lies between (10 and 22) inclusive, the lipids being defined as esters of glycerol (propane 1,2,3-triol) with fatty acids, also including 1,2-di-O-acylglycerol joined at oxygen (3) by a glycosidic linkage to a carbohydrate, also derivatives of glycerol in which one hydroxy group, commonly but not necessarly primary, is esterified with fatty acids, and execluding those organic compounds consisting of a trisaccharide repeating unit with oligosaccharide side chains and acyl or amine linked fatty acids.

  一种产品及其用途，用于刺激和/或调节动物和人类的免疫反应，包括具有甘油骨架的脂质，其携带至少一个烷基或酰基链，其中脂质为磷脂类、糖脂类或中性脂质，饱和或不饱和，碳原子数在(10和22)之间，脂质被定义为甘油(丙烷-1,2,3-三醇)与脂肪酸的酯，还包括通过氧(3)连接到碳水化合物的糖苷键的1,2-二-O-酰基甘油，以及甘油的衍生物，其中一个羟基团，通常但不一定是主要的，与脂肪酸酯化，不包括由三糖重复单元和寡糖侧链以及酰基或胺链脂肪酸组成的有机化合物。
• Functional associative coatings for nanoparticles
  申请人：Hainfeld James F.

  公开号：US20080089836A1

  公开（公告）日：2008-04-17

  Described herein are nanoparticles that are coated with a bilayer of molecules formed from surface binding molecules and amphiphatic molecules. The bilayer coating self assembles on the nanoparticles from readily available materials/molecules. The modular design of the bilayer coated nanoparticles provides a means for readily and efficiently optimizing the properties of the bilayer coated nanoparticle compositions. Also described herein are uses of such nanoparticles in medicine, laboratory techniques, industrial and commerical applications.

  本文描述了一种纳米颗粒，其表面涂覆有由表面结合分子和两亲分子形成的双层分子层。该双层涂层可以自组装在纳米颗粒上，使用易得的材料/分子。双层涂层纳米颗粒的模块化设计提供了一种方便和高效地优化其性质的方法。此外，本文还描述了这种纳米颗粒在医学、实验室技术、工业和商业应用中的用途。
• Solid oil-based candles
  申请人：CLILCO COSMETICS & PHARMACEUTICALS LTD.

  公开号：EP0685554A1

  公开（公告）日：1995-12-06

  A composition for use in illumination, including at least one oil; and at a gelatinizing composition consisting exclusively of at least one gelatinizing agent having 15 or more carbons, selected from the group consisting of fatty acids and fatty acid derivatives, in a concentration between about 0.3 and 50 mass percent, sufficient to gelatinize the at least one oil. In particular, the oil is olive oil and the gelatinizing agent is a fatty alcohol selected from the group consisting of C-40 straight chain fatty alcohol (CH₃(CH₂CH₂)₁₉CH₂OH), C-50 straight chain fatty alcohol (CH₃(CH₂CH₂)₂₄CH₂OH) and 12-Hydroxy stearic acid.

  一种用于照明的组合物，包括至少一种油；以及一种凝胶化组合物，该组合物完全由至少一种具有 15 个或更多碳原子的凝胶化剂组成，该凝胶化剂选自由脂肪酸和脂肪酸衍生物组成的组，其浓度在约 0.3 至 50 质量百分数之间，足以使至少一种油凝胶化。具体来说，油是橄榄油，糊化剂是脂肪醇，选自由 C-40 直链脂肪醇（CH₃(CH₂CH₂)₁₉CH₂OH）组成的组、C-50 直链脂肪醇（CH₃(CH₂CH₂)₂₄CH₂OH）和 12-羟基硬脂酸。
• Probe compound for detecting and isolating enzymes and means and methods using the same
  申请人：Helmholtz-Zentrum für Infektionsforschung GmbH

  公开号：EP2230312A1

  公开（公告）日：2010-09-22

  The present invention relates to a probe compound that can comprise any substrate or metabolite of an enzymatic reaction in addition to an indicator component, such as, for example, a fluorescence dye, or the like. Moreover, the present invention relates to means for detecting enzymes in form of an array, which comprises any number of probe compounds of the invention which each comprise a different metabolite of interconnected metabolites representing the central pathways in all forms of life. Moreover, the present invention relates to a method for detecting enzymes involving the application of cell extracts or the like to the array of the invention which leads to reproducible enzymatic reactions with the substrates. These specific enzymatic reactions trigger the indicator (e.g. a fluorescence signal) and bind the enzymes to the respective cognate substrates. Moreover, the invention relates to means for isolating enzymes in form of nanoparticles coated with the probe compound of the invention. The immobilisation of the cognate substrates or metabolites on the surface of nanoparticles by means of the probe compounds allows capturing and isolating the respective enzyme, e.g. for subsequent sequencing.

  本发明涉及一种探针化合物，它可以包括酶反应的任何底物或代谢物，此外还包括指示成分，例如荧光染料或类似物。此外，本发明还涉及以阵列形式检测酶的方法，该阵列由任意数量的本发明探针化合物组成，每种探针化合物由代表所有生命形式中中心途径的相互关联的代谢物中的不同代谢物组成。此外，本发明还涉及一种检测酶的方法，该方法涉及将细胞提取物或类似物应用于本发明的阵列，从而导致与底物发生可重复的酶反应。这些特定的酶反应会触发指示剂（如荧光信号），并将酶与各自的同源底物结合。此外，本发明还涉及以涂覆有本发明探针化合物的纳米颗粒形式分离酶的方法。通过探针化合物将同源底物或代谢物固定在纳米颗粒表面，可以捕获和分离相应的酶，例如用于后续测序。
• Metathesized triacylglycerol polyols for use in polyurethane applications and their related properties
  申请人：Trent University

  公开号：US10000601B2

  公开（公告）日：2018-06-19

  Metathesized triacylglycerol polyols and their related physical and thermal properties are disclosed. Such metathesized triacylglycerol polyols are also used as a component of polyurethane applications, including polyurethane foams.

  公开了偏聚三酰甘油多元醇及其相关的物理和热性能。这种偏聚三酰甘油多元醇还可用作聚氨酯应用（包括聚氨酯泡沫）的成分。