Halkendin | 27272-64-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: Halkendin
• 英文别名: 5,6-dimethoxyfuro[3,2-g]chromen-7-one
• CAS: 27272-64-6
• 化学式: C₁₃H₁₀O₅
• 分子量: 246.219
• InChiKey: NYELECLICIMRBA-UHFFFAOYSA-N

物化性质

• 沸点：
  476.1±45.0 °C(Predicted)
• 密度：
  1.38±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  57.9
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• PEG-lipid containing formulations
  申请人：——

  公开号：US20040013717A1

  公开（公告）日：2004-01-22

  The invention is generally related to the field of drug delivery systems comprising micelles. These systems may be used to deliver a photosensitizer as a pharmaceutical, agricultural, or industrial agent. The photosensitizer-containing formulations and compositions of the invention comprise one or more PEG-containing phospholipids. Furthermore, the invention relates to processes for the production of, and application of, said formulations and compositions as a drug delivery system.

  本发明一般涉及由胶束组成的给药系统领域。这些系统可用于递送光敏剂作为药物、农业或工业制剂。本发明的含光敏剂制剂和组合物包含一种或多种含 PEG 的磷脂。此外，本发明还涉及生产和应用上述制剂和组合物作为给药系统的工艺。
• Photodynamic therapy for the treatment of hair loss
  申请人：——

  公开号：US20040015214A1

  公开（公告）日：2004-01-22

  Photodynamic therapy (PDT) is used to stimulate and/or restore hair growth in areas of hair loss. Methods and compositions relating to PDT treatment for alopecia are disclosed. In light of PDT use to remove unwanted hair by inactivating or destroying hair follicles or destroying the tissue feeding the hair follicles, such methods and compositions relate to a surprising and unexpected discovery. PDT permits a means to treat conditions relating to hair loss such as androgenic alopecia, alopecia areata and drug-induced alopecia.

  光动力疗法（PDT）用于刺激和/或恢复脱发区域的毛发生长。本文公开了与光动力疗法治疗脱发有关的方法和组合物。鉴于 PDT 可通过灭活或破坏毛囊或破坏毛囊供养组织来去除不想要的毛发，这种方法和组合物涉及一项令人惊讶和意想不到的发现。光致脱色疗法可以治疗与脱发有关的疾病，如雄激素性脱发、斑秃和药物性脱发。
• PROCEDE DE PRODUCTION DE METABOLITES A PARTIR DE VEGETAUX EN CULTURE HORS SOL
  申请人：INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA)

  公开号：EP1227714A1

  公开（公告）日：2002-08-07
• PHOTODYNAMIC THERAPY FOR THE TREATMENT OF HAIR LOSS
  申请人：QLT Inc.

  公开号：EP1443964A1

  公开（公告）日：2004-08-11
• MICELLE COMPOSITIONS CONTAINING PEGYLATED PHOSPHOLIPIDS AND A PHOTOSENSITIZER
  申请人：THE GOVERNORS OF THE UNIVERSITY OF ALBERTA

  公开号：EP1465590A2

  公开（公告）日：2004-10-13