Urothion | 17801-77-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 蝶啶及其衍生物
• 英文名称: Urothion
• 英文别名: (+/-)-Urothione；2-amino-7-(1,2-dihydroxyethyl)-6-methylsulfanyl-3H-thieno[3,2-g]pteridin-4-one
• CAS: 17801-77-3
• 化学式: C₁₁H₁₁N₅O₃S₂
• 分子量: 325.372
• InChiKey: RPUOVNROVSNPBD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  187
• 氢给体数：
  4
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  Urothion 在 periodate 作用下， 生成 Urothion-aldehyd
  参考文献：
  名称：

  尿毒症

  摘要：

  DOI：

  10.1016/s0040-4039(01)89544-7
• 作为产物：
  描述：

  7-Bromo-6-(tert-butoxyacetyl)-2-cyano-3-<<(dimethylamino)methylene>amino>thieno<2,3-b>pyrazine 在 sodium tetrahydroborate 、 硫酸 、 sodium methylate 、 sodium hydride 、 对甲苯磺酸 、 三氟乙酸 作用下， 以 四氢呋喃 、 甲醇 、 乙醇 为溶剂， 反应 6.5h， 生成 Urothion
  参考文献：
  名称：

  Studies on the molybdenum cofactor. An unequivocal total synthesis of (.+-.)-urothione

  摘要：

  DOI：

  10.1021/ja00183a043

文献信息

• METHOD OF INHIBITING OXIDATION, WATER CAPABLE OF INHIBITING OXIDATION AND USE THEREOF
  申请人：MIZ Co., Ltd.

  公开号：EP1550637A1

  公开（公告）日：2005-07-06

  The objective of the present invention is to provide an antioxidation method and antioxidant-functioning water that can anticipate high benchmarks of safety on the antioxidation subject such as the human body and reduced environmental burden. An antioxidation method and antioxidant- functioning water that can transform or maintain an antioxidation subject, which is in an oxidation state due to a deficiency of electrons or needs to be protected from oxidation, into a reduced state where electrons are filled by promoting the breaking reaction of molecular hydrogen used as a substrate included in the hydrogen- dissolved water into a product of active hydrogen through a process employing a catalyst, which is a precious metal colloid or a hydrogen oxidation/ reduction enzyme (except for those already existing in a living organism), on the hydrogen-dissolved water.

  本发明的目的是提供一种抗氧化方法和抗氧化功能水，可以预测抗氧化主体（如人体）的高安全标准，并减少环境负担。一种抗氧化方法和抗氧化功能水，可以将处于氧化状态的抗氧化主体（由于电子不足或需要保护免受氧化）转化或维持在还原状态，通过使用催化剂（贵金属胶体或氢氧化还原酶（除已存在于生物体内的酶））在氢溶解水中，促进分子氢的断裂反应，将其转化为活性氢产物。
• KYNURENINE 3-HYDROXYLASE INHIBITORS FOR THE TREATMENT OF DIABETES
  申请人：Merck Patent GmbH

  公开号：EP1581215B1

  公开（公告）日：2010-02-17
• DIAGNOSTISCHES IN-VITRO-VERFAHREN
  申请人：Universität zu Köln

  公开号：EP3022315A1

  公开（公告）日：2016-05-25
• Method of inhibiting oxidation, water capable of inhibiting oxidation and use thereof
  申请人：Yanagihara Tomoyuki

  公开号：US20050170011A1

  公开（公告）日：2005-08-04

  The objective of the present invention is to provide an antioxidation method and antioxidant-functioning water that can anticipate high benchmarks of safety on the antioxidation subject such as the human body and reduced environmental burden. An antioxidation method and antioxidant-functioning water that can transform or maintain an antioxidation subject, which is in an oxidation state due to a deficiency of electrons or needs to be protected from oxidation, into a reduced state where electrons are filled by promoting the breaking reaction of molecular hydrogen used as a substrate included in the hydrogen-dissolved water into a product of active hydrogen through a process employing a catalyst, which is a precious metal colloid or a hydrogen oxidation/reduction enzyme (except for those already existing in a living organism), on the hydrogen-dissolved water.
• Pharmacologic-functioning water and usage of the same
  申请人：Yanagihara Tomoyuki

  公开号：US20070148256A1

  公开（公告）日：2007-06-28

  The present invention provides a new pharmacologic-functioning water demonstrating pharmacologic function without any side effects, and usage of the same. The pharmacologic-functioning water, which demonstrates pharmacologic function without any side effects and includes antioxidant-functioning water as an active principle containing hydrogen-dissolved water, which is made up of molecular hydrogen used as a substrate that is included in raw water, and a precious metal colloid, which is included in the hydrogen-dissolved water and catalyzes the breaking reaction of the molecular hydrogen into a product of atomic hydrogen, is used for preventing and/or treating diseases.