1,2,3-tris-linolenoyloxy-propane | 14465-68-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油脂
• 英文名称: 1,2,3-tris-linolenoyloxy-propane
• 英文别名: 1,2,3-Tris-linolenoyloxy-propan；2,3-Di(octadeca-9,12,15-trienoyloxy)propyl octadeca-9,12,15-trienoate
• CAS: 14465-68-0
• 化学式: C₅₇H₉₂O₆
• 分子量: 873.354
• InChiKey: UBEIMDKGOYBUKT-UHFFFAOYSA-N

物化性质

• 熔点：
  -23-24 °C
• 沸点：
  814.4±65.0 °C(Predicted)
• 密度：
  0.94 g/mL at 20 °C(lit.)
• 溶解度：
  DMF：10mg/mL；乙醇：10mg/mL；乙醇:PBS(pH 7.2) (1:1): 500μg/ml

计算性质

• 辛醇/水分配系数(LogP)：
  18.3
• 重原子数：
  63
• 可旋转键数：
  47
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.631
• 拓扑面积：
  78.9
• 氢给体数：
  0
• 氢受体数：
  6

安全信息

• WGK Germany：
  3
• 储存条件：
  -20°C

SDS

---

Section 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
Product identifiers
Product name : Glyceryl trilinolenate
CAS-No. : 14465-68-0
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances

---

Section 2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to EC-directives 67/548/EEC or 1999/45/EC.
Label elements
The product does not need to be labelled in accordance with EC directives or respective national laws.
Other hazards - none

---

Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substances
Synonyms : 1,2,3-Tri-(cis,cis,cis-9,12,15-octadecatrienoyl)glycerol
1,2,3-Trilinolenoylglycerol
Glycerol trilinolenate
Trilinolenin
Formula : C57H92O6 C57H92O6
Molecular Weight : 873,34 g/mol

---

Section 4. FIRST AID MEASURES
Description of first aid measures
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration.
In case of skin contact
Wash off with soap and plenty of water.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.
Most important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
no data available

---

Section 5. FIREFIGHTING MEASURES
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

---

Section 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Avoid breathing vapors, mist or gas.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Keep in suitable, closed containers for disposal.
Reference to other sections
For disposal see section 13.

---

Section 7. HANDLING AND STORAGE
Precautions for safe handling
no data available
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature: -20 °C
Store under inert gas. Air sensitive.
Specific end uses
no data available

---

Section 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
General industrial hygiene practice.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards
such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Respiratory protection not required. For nuisance exposures use type OV/AG (US) or type ABEK
(EU EN 14387) respirator cartridges. Use respirators and components tested and approved under
appropriate government standards such as NIOSH (US) or CEN (EU).

---

Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Information on basic physical and chemical properties
a) Appearance Form: liquid
Colour: colourless
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing no data available
point
f) Initial boiling point and no data available
boiling range
g) Flash point no data available
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density 0,94 g/cm3 at 20 °C
n) Water solubility no data available
o) Partition coefficient: n- no data available
octanol/water
p) Autoignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
no data available

---

Section 10. STABILITY AND REACTIVITY
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
Other decomposition products - no data available

---

Section 11. TOXICOLOGICAL INFORMATION
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation May be harmful if inhaled. May cause respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through skin. May cause skin irritation.
Eyes May cause eye irritation.
Additional Information
RTECS: Not available

---

Section 12. ECOLOGICAL INFORMATION
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
no data available
Other adverse effects
no data available

---

Section 13. DISPOSAL CONSIDERATIONS
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contaminated packaging
Dispose of as unused product.

---

Section 14. TRANSPORT INFORMATION
UN number
ADR/RID: - IMDG: - IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
Packaging group
ADR/RID: - IMDG: - IATA: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
no data available

---

---

SECTION 15 - REGULATORY INFORMATION
N/A

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  1,2,3-tris-linolenoyloxy-propane 、 2-乙烯氧基乙醇 在 potassium hydroxide 作用下， 以7%的产率得到
  参考文献：
  名称：

  Living carbocationic polymerization of a vinyl ether monomer derived from soybean oil, 2-(vinyloxy)ethyl soyate

  摘要：

  一种新颖的乙烯基醚单体通过碱催化的转酯化反应，从大豆油中得到，该反应是将2-(乙烯氧基)乙醇与大豆油进行反应。对这种单体的阳离子聚合进行了研究，该单体称为2-(乙烯氧基)乙基大豆酸酯（2-VOES），聚合系统使用了二官能团阳离子引发剂、作为共同引发剂的三氯化铝乙基、氯化铝胺和溶剂乙苯，聚合温度为0°C。在该聚合系统中，聚合反应对单体的一阶反应，并且分子量随着单体转化率线性增加。此外，所得到聚合物的分子量分布低于1.2。当向聚合反应中加入新鲜单体时，该聚合反应已达到约90%的单体转化率，结果导致分子量的进一步增加，而分子量分布没有增加。这些结果表明，聚合反应是一种活性聚合反应，这将在未来实现良好定义的聚合物结构，如三嵌段共聚物。

  DOI：

  10.1039/c3gc40605a

文献信息

• Living carbocationic polymerization of a vinyl ether monomer derived from soybean oil, 2-(vinyloxy)ethyl soyate
  作者：Andrey Chernykh、Samim Alam、Anurad Jayasooriya、James Bahr、Bret J. Chisholm

  DOI：10.1039/c3gc40605a

  日期：——

  A novel vinyl ether monomer was produced from soybean oil by base-catalyzed transesterification of 2-(vinyloxy)ethanol with soybean oil. The cationic polymerization of this monomer, which is being referred to as 2-(vinyloxy)ethyl soyate (2-VOES), was investigated using a polymerization system involving a difunctional cationogen, ethylaluminum sesquichloride as the coinitiator, toluene as the solvent, and a polymerization temperature of 0 °C. With this polymerization system, the polymerization was first order with respect to monomer and molecular weight increased linearly with monomer conversion. Further, the molecular weight distribution of the polymers obtained were below 1.2. The addition of fresh monomer to a polymerization that had reach approximately 90 percent monomer conversion resulted in a further increase in molecular weight without an increase in molecular weight distribution. These results indicate that the polymerization was a living polymerization, which will enable well-defined polymer architectures, such as triblock copolymers, to be produced in the future.

  一种新颖的乙烯基醚单体通过碱催化的转酯化反应，从大豆油中得到，该反应是将2-(乙烯氧基)乙醇与大豆油进行反应。对这种单体的阳离子聚合进行了研究，该单体称为2-(乙烯氧基)乙基大豆酸酯（2-VOES），聚合系统使用了二官能团阳离子引发剂、作为共同引发剂的三氯化铝乙基、氯化铝胺和溶剂乙苯，聚合温度为0°C。在该聚合系统中，聚合反应对单体的一阶反应，并且分子量随着单体转化率线性增加。此外，所得到聚合物的分子量分布低于1.2。当向聚合反应中加入新鲜单体时，该聚合反应已达到约90%的单体转化率，结果导致分子量的进一步增加，而分子量分布没有增加。这些结果表明，聚合反应是一种活性聚合反应，这将在未来实现良好定义的聚合物结构，如三嵌段共聚物。