2-hydroxy-24-keto-octacosanolide

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: 2-hydroxy-24-keto-octacosanolide
• 英文别名: 3-hydroxy-oxacyclononacosane-2,25-dione
• 化学式: C₂₈H₅₂O₄
• 分子量: 452.718
• InChiKey: XHLPRIJMQZUNTK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.9
• 重原子数：
  32
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-hydroxy-24-keto-octacosanolide 在 吡啶 、 sodium methylate 作用下， 反应 2.0h， 生成 2,28-Diacetoxy-24-oxo-octacosanoic acid methyl ester
  参考文献：
  名称：

  New macrolactones from the defensive salivary secretion of soldiers of the african termite Pseudacanthotermes spiniger

  摘要：

  The salivary defensive secretion of large soldier termites of the species Pseudacanthotermes spiniger contains two novel macrocyclic lactones [22-keto-hexacosanolide (2) and 2-hydroxy-24-keto-octacosanolide (3)] together with the already known macrolactone hexacosanolide (1). In addition, the secretion contains important amounts of a polysaccharide based mainly upon beta-glucoypyranose, beta-glucosamine and N-acetyl-beta-glucosamine in equal amount. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01961-9

文献信息

• New macrolactones from the defensive salivary secretion of soldiers of the african termite Pseudacanthotermes spiniger
  作者：Valérie Plasman、Désiré Daloze、Jean-Claude Braekman、Sophie Connétable、Alain Robert、Christian Bordereau

  DOI：10.1016/s0040-4039(99)01961-9

  日期：1999.12

  The salivary defensive secretion of large soldier termites of the species Pseudacanthotermes spiniger contains two novel macrocyclic lactones [22-keto-hexacosanolide (2) and 2-hydroxy-24-keto-octacosanolide (3)] together with the already known macrolactone hexacosanolide (1). In addition, the secretion contains important amounts of a polysaccharide based mainly upon beta-glucoypyranose, beta-glucosamine and N-acetyl-beta-glucosamine in equal amount. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.