5-Ethyl-5-(3-hydroxy-1-methylbutyl)-barbituric Acid | 13865-71-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 5-Ethyl-5-(3-hydroxy-1-methylbutyl)-barbituric Acid
• 英文别名: rac.-5-Ethyl-5-(3-hydroxy-1-methyl-butyl)-barbitursaeure；(1'RS,3'SR)-5-Ethyl-5-(3'-hydroxy-1'-methyl-butyl)-barbitursaeure；(1'RS,3'RS)-5-Ethyl-5-(3'-hydroxy-1'-methyl-butyl)-barbitursaeure；5-ethyl-5-(3-hydroxy-1-methyl-butyl)-pyrimidine-2,4,6-trione；2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-hydroxy-1-methylbutyl)-；5-ethyl-5-(4-hydroxypentan-2-yl)-1,3-diazinane-2,4,6-trione
• CAS: 13865-71-9
• 化学式: C₁₁H₁₈N₂O₄
• 分子量: 242.275
• InChiKey: XYOPMDJVSWQZTM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  95.5
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• US4036823A
  申请人：——

  公开号：US4036823A

  公开（公告）日：1977-07-19
• [EN] BIOMARKERS OF REDUCED INSULIN ACTION<br/>[FR] MARQUEURS BIOLOGIQUES D'UNE ACTION RÉDUITE DE L'INSULINE
  申请人：MAYO FOUNDATION

  公开号：WO2012058298A1

  公开（公告）日：2012-05-03

  This document provides methods and materials for assessing metabolic disorders related to reduced insulin action (e.g. insulin resistance or insulin deficiency) in a mammal (e.g. human). For example, methods and materials for assessing insulin resistance, risk of developing insulin resistance and monitoring efficacy of insulin resistance treatment are provided.

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