8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen
• 英文别名: 9-(3-ethoxy-2-hydroxy-3-methylbutoxy)furo[3,2-g]chromen-7-one
• 化学式: C₁₈H₂₀O₆
• 分子量: 332.3
• InChiKey: ZQAHVKVXUSYIBF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  78.1
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• NEURO-PROTECTIVE EFFECTS OF ADELOSTEMMA GRACILLIMUM AND ITS ISOLATED COMPOUNDS
  申请人：Ip Nancy Yuk-yu

  公开号：US20130079293A1

  公开（公告）日：2013-03-28

  Isolated compounds from adelostemma gracillimum refined fractions and compositions containing the compounds are provided by the present invention. Adelostemma gracillimum refined fractions and the extraction process thereof are also provided by the present invention. The uses of the compounds and the adelostemma gracillimum refined fractions for inhibiting the activities of NMDA receptor or amyloid-beta peptide, for improving memory, and for treating neurodegenerative diseases, neuropathological conditions or epilepsy are further provided by the present invention.
• US9150608B2
  申请人：——

  公开号：US9150608B2

  公开（公告）日：2015-10-06
• [EN] NEURO-PROTECTIVE EFFECTS OF ADELOSTEMMA GRACILLIMUM AND ITS ISOLATED COMPOUNDS<br/>[FR] EFFETS NEUROPROTECTEURS D'ADELOSTEMMA GRACILLIUM ET COMPOSÉS ISOLÉS À PARTIR DE CETTE DERNIÈRE
  申请人：BIOTECHNOLOGY RES CORP LTD

  公开号：WO2011114220A1

  公开（公告）日：2011-09-22

  Isolated compounds from adelostemma gracillimum refined fractions and compositions containing the compounds are provided by the present invention. Adelostemma gracillimum refined fractions and the extraction process thereof are also provided by the present invention. The uses of the compounds and the adelostemma gracillimum refined fractions for inhibiting the activities of NMDA receptor or amyloid-beta peptide, for improving memory, and for treating neurodegenerative diseases, neuropathological conditions or epilepsy are further provided by the present invention.