4-[5-(3,5-Dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-N'-methoxy-2,N,N-trimethyl-benzamidine | 1233232-14-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[5-(3,5-Dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-N'-methoxy-2,N,N-trimethyl-benzamidine
• 英文别名: 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N'-methoxy-N,N,2-trimethylbenzenecarboximidamide
• CAS: 1233232-14-8
• 化学式: C₂₁H₂₀Cl₂F₃N₃O₂
• 分子量: 474.31
• InChiKey: GSFKLJONWRGOME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  46.4
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-N-hydroxy-2,N,N-trimethyl-benzamidine 、 硫酸二甲酯 在 lithium hydroxide 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 以83%的产率得到4-[5-(3,5-Dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-N'-methoxy-2,N,N-trimethyl-benzamidine
  参考文献：
  名称：

  [EN] SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS
  [FR] COMPOSÉS AMIDINE SUBSTITUÉS DESTINÉS À LUTTER CONTRE LES ANIMAUX NUISIBLES

  摘要：

  该发明涉及式(I)的取代胺基化合物，其对映异构体、顺反异构体及其盐，以及包含这种化合物的组合物。该发明还涉及使用这些取代胺基化合物、它们的盐或包含它们的组合物来对抗动物害虫。此外，该发明还涉及应用这种取代胺基化合物的方法。本发明的取代胺基化合物由式(I)定义，其中A1至A4、B1至B3、R1至R3、(R4)p、(R5)q、X和Y的定义如描述中所述。

  公开号：

  WO2010072602A1

文献信息

• Substituted Amidine Compounds for Combating Animal Pests
  申请人：Kaiser Florian

  公开号：US20110257011A1

  公开（公告）日：2011-10-20

  The invention relates to substituted amidine compounds of formula (I), to the enantiomers, diastereomers and salts thereof and to compositions comprising such compounds. The invention also relates to the use of the substituted amidine compounds, of their salts or of compositions comprising them for combating animal pests. Furthermore the invention relates also to methods of applying such substituted amidine compounds. The substituted amidine compounds of the present invention are defined by the following formula I: wherein A 1 to A 4 , B 1 to B 3 , R 1 to R 3 , (R 4 ) p , (R 5 ) q , X and Y are defined as in the description.

  本发明涉及公式（I）的取代氨基化合物，其对映异构体、对映异构体和其盐以及含有这种化合物的组合物。本发明还涉及使用取代氨基化合物、其盐或含有它们的组合物来对抗动物害虫。此外，本发明还涉及应用这种取代氨基化合物的方法。本发明的取代氨基化合物由以下公式I定义：其中A1到A4，B1到B3，R1到R3，（R4）p，（R5）q，X和Y如描述中所定义。
• Substituted amidine compounds for combating animal pests
  申请人：Kaiser Florian

  公开号：US08633134B2

  公开（公告）日：2014-01-21

  The invention relates to substituted amidine compounds of formula (I), to the enantiomers, diastereomers and salts thereof and to compositions comprising such compounds. The invention also relates to the use of the substituted amidine compounds, of their salts or of compositions comprising them for combating animal pests. Furthermore the invention relates also to methods of applying such substituted amidine compounds. The substituted amidine compounds of the present invention are defined by the following formula I: wherein A1 to A4, B1 to B3, R1 to R3, (R4)p, (R5)q, X and Y are defined as in the description.

  本发明涉及公式（I）的取代酰胺化合物，其对映异构体、顺反异构体和其盐以及包含这些化合物的组合物。本发明还涉及使用所述取代酰胺化合物、其盐或包含它们的组合物来对抗动物害虫。此外，本发明还涉及应用这种取代酰胺化合物的方法。本发明所述的取代酰胺化合物由以下公式I定义：其中A1至A4、B1至B3、R1至R3、（R4）p、（R5）q、X和Y如描述中所定义。
• [EN] SUBSTITUTED AMIDINE COMPOUNDS FOR COMBATING ANIMAL PESTS<br/>[FR] COMPOSÉS AMIDINE SUBSTITUÉS DESTINÉS À LUTTER CONTRE LES ANIMAUX NUISIBLES
  申请人：BASF SE

  公开号：WO2010072602A1

  公开（公告）日：2010-07-01

  The invention relates to substituted amidine compounds of formula (I), to the enantiomers, diastereomers and salts thereof and to compositions comprising such compounds. The invention also relates to the use of the substituted amidine compounds, of their salts or of compositions comprising them for combating animal pests. Furthermore the invention relates also to methods of applying such substituted amidine compounds. The substituted amidine compounds of the present invention are defined by formula (I) wherein A1 to A4, B1 to B3, R1 to R3, (R4)p, (R5)q, X and Y are defined as in the description.

  该发明涉及式(I)的取代胺基化合物，其对映异构体、顺反异构体及其盐，以及包含这种化合物的组合物。该发明还涉及使用这些取代胺基化合物、它们的盐或包含它们的组合物来对抗动物害虫。此外，该发明还涉及应用这种取代胺基化合物的方法。本发明的取代胺基化合物由式(I)定义，其中A1至A4、B1至B3、R1至R3、(R4)p、(R5)q、X和Y的定义如描述中所述。