N-diphenylphosphinothioyl-3-methyl-1,3-thiazol-2-imine | 1160735-44-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-diphenylphosphinothioyl-3-methyl-1,3-thiazol-2-imine
• CAS: 1160735-44-3
• 化学式: C₁₆H₁₅N₂PS₂
• 分子量: 330.414
• InChiKey: ABFWQENKOHVZPS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  73
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  diphenylphosphinous acid 3-methyl-3H-thiazol-2-ylideneamide 在 1,2,3,4,5,6,7,8-八硫杂环辛烷 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 48.0h， 生成 N-diphenylphosphinothioyl-3-methyl-1,3-thiazol-2-imine
  参考文献：
  名称：

  Novel Synthetic Approach to Thiophosphinates Incorporating Different N-Heterocycles

  摘要：

  Eight new cycloiminylidenamidothiophosphinates incorporating pyridine, pyrimidine, thiazole, and benzothiazole heterocycles were synthesized by phosphorylation of the quaternary iminium salts of the heterocycles by diphenylchlorophosphine followed by in situ sulfurization by elemental sulfur. Crystalline solid products were well characterized by elemental analysis and NMR spectroscopy.

  DOI：

  10.1080/10426500802060735

文献信息

• Novel Synthetic Approach to Thiophosphinates Incorporating Different N-Heterocycles
  作者：Vijaya Kabra、Sunita Mitharwal、Arpana Meel、Suman Tanwar

  DOI：10.1080/10426500802060735

  日期：2008.11.7

  Eight new cycloiminylidenamidothiophosphinates incorporating pyridine, pyrimidine, thiazole, and benzothiazole heterocycles were synthesized by phosphorylation of the quaternary iminium salts of the heterocycles by diphenylchlorophosphine followed by in situ sulfurization by elemental sulfur. Crystalline solid products were well characterized by elemental analysis and NMR spectroscopy.