(E)-1-(bromo(1,3-dithian-2-ylidene)methyl)-2-(4-fluorophenyl)diazene | 1562209-99-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-1-(bromo(1,3-dithian-2-ylidene)methyl)-2-(4-fluorophenyl)diazene
• CAS: 1562209-99-7
• 化学式: C₁₁H₁₀BrFN₂S₂
• 分子量: 333.248
• InChiKey: SNNDMFLVXFIPGD-CCEZHUSRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  17.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  24.72
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  2-methyl-5,6-dihydro-4H-1,3-dithianylium tetrafluorborate 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 二氯甲烷 、 乙腈 为溶剂， 反应 1.33h， 生成 (E)-1-(bromo(1,3-dithian-2-ylidene)methyl)-2-(4-fluorophenyl)diazene
  参考文献：
  名称：

  Reactions of Resin-Bound Triazenes with Dithianylium Tetrafluoroborates: Efficient Synthesis of α-Azo Ketene Dithioacetals and Related Hydrazones

  摘要：

  The conversion of dithianylium cations into alpha-azo ketene dithioacetals via addition of polymer-bound diazonium precursors is shown. This new procedure allows the synthesis of a-azo ketene dithioacetals in one step within 2-90 min at rt and yields highly pure compounds that do not have to be purified in most cases. The alpha-azo ketene dithioacetals obtained have been shown to be valuable intermediates for the synthesis of hydrazones, alpha-halogenated alpha-azo ketene dithioacetals, and azo-functionalized dienes.

  DOI：

  10.1021/ol4037133

文献信息

• Reactions of Resin-Bound Triazenes with Dithianylium Tetrafluoroborates: Efficient Synthesis of α-Azo Ketene Dithioacetals and Related Hydrazones
  作者：Nicole Jung、Bettina Stanek、Simone Gräßle、Martin Nieger、Stefan Bräse

  DOI：10.1021/ol4037133

  日期：2014.2.21

  The conversion of dithianylium cations into alpha-azo ketene dithioacetals via addition of polymer-bound diazonium precursors is shown. This new procedure allows the synthesis of a-azo ketene dithioacetals in one step within 2-90 min at rt and yields highly pure compounds that do not have to be purified in most cases. The alpha-azo ketene dithioacetals obtained have been shown to be valuable intermediates for the synthesis of hydrazones, alpha-halogenated alpha-azo ketene dithioacetals, and azo-functionalized dienes.