2,3-dimethylnonanoyl chloride | 88663-35-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: 2,3-dimethylnonanoyl chloride
• 英文别名: 2,3-Dimethylnonanoyl chloride
• CAS: 88663-35-8
• 化学式: C₁₁H₂₁ClO
• 分子量: 204.74
• InChiKey: KSVYUCRAUPFPST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  13
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  炔诺酮 、 2,3-dimethylnonanoyl chloride 以 吡啶 为溶剂， 反应 75.0h， 生成 norethisterone 2,3-dimethylnonanoate
  参考文献：
  名称：

  Long-acting contraceptive agents: Esters of norethisterone with α- and/or β-chain branching

  摘要：

  The synthesis of eighteen esters of norethisterone (17 alpha-ethynyl-17 beta-hydroxyestr-4-en-3-one) is described. These all possess some form of alpha- and/or beta-substitution in the ester side-chain. The work was undertaken in order to evaluate any long-acting fertility control effect intrinsic in such compounds. A pentamethyl disiloxy ether was also included in the group of substances prepared for testing because of its similar substitution pattern.

  DOI：

  10.1016/0039-128x(83)90096-x

文献信息

• Long-acting contraceptive agents: Esters of norethisterone with α- and/or β-chain branching
  作者：T.G. Watson、M. Hosking、J.E. Herz、J.V. Torres、J. Muller、A. Murillo、S. Cruz、A. Shafiee、M. Vossoghi、F. Savabi、S. Sotheeswaran、V. Puvanesarajah

  DOI：10.1016/0039-128x(83)90096-x

  日期：1983.3

  The synthesis of eighteen esters of norethisterone (17 alpha-ethynyl-17 beta-hydroxyestr-4-en-3-one) is described. These all possess some form of alpha- and/or beta-substitution in the ester side-chain. The work was undertaken in order to evaluate any long-acting fertility control effect intrinsic in such compounds. A pentamethyl disiloxy ether was also included in the group of substances prepared for testing because of its similar substitution pattern.