Nickel(II)–salen or nickel(II)–salphen catalyzed α-alkylation of ketones and nitriles with primary alcohols is reported. Various α-alkylated ketones and nitriles were obtained in high yields through a borrowing hydrogen strategy by using 1–3 mol% of nickel catalyst and a catalytic amount of NaOH (5–10 mol%) under aerobic conditions.
报道了镍 ( II )–salen 或镍 ( II )–salphen 催化酮和腈与伯醇的 α-烷基化。通过在有氧条件下使用 1-3 mol% 的镍催化剂和催化量的 NaOH (5-10 mol%),通过借氢策略以高收率获得各种 α-烷基化酮和腈。
Kundu, Arijit; Bhattacharyya, Bhaswati; Dhara, Kaliprasanna, Journal of the Indian Chemical Society, 2012, vol. 89, # 12, p. 1711 - 1722