5-(3-bromopropyl)-3,3,7,7-tetramethyl[1,2,5]perhydrodithiazepine | 361553-02-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 5-(3-bromopropyl)-3,3,7,7-tetramethyl[1,2,5]perhydrodithiazepine
• 英文别名: 5-(3-Bromopropyl)-3,3,7,7-tetramethyl-1,2,5-dithiazepane；5-(3-bromopropyl)-3,3,7,7-tetramethyl-1,2,5-dithiazepane
• CAS: 361553-02-8
• 化学式: C₁₁H₂₂BrNS₂
• 分子量: 312.338
• InChiKey: WERJXTHFNILMTH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  53.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-(3-bromopropyl)-3,3,7,7-tetramethyl[1,2,5]perhydrodithiazepine 在 sodium hydroxide 、 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 19.0h， 生成 1-[[3-(2-Chloro-phenothiazin-10-yl)-propyl]-(2-mercapto-2-methyl-propyl)-amino]-2-methyl-propane-2-thiol
  参考文献：
  名称：

  Synthesis of oxorhenium(V) and oxotechnetium(V) [SN(R)S/S] mixed ligand complexes containing a phenothiazine moiety on the tridentate SN(R)S ligand

  摘要：

  Two oxorhenium and two oxotechnetium [SN(R)S/S] mixed ligand complexes bearing the phenothiazine moiety on the tridentate ligand SN(R)S have been synthesized and characterized. The corresponding complexes at tracer level (Tc-99m) have also been prepared. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(01)00309-2
• 作为产物：
  描述：

  3-溴丙胺 、 2,2'-dithiobis(2-methylpropanal) 在 sodium cyanoborohydride 、 溶剂黄146 作用下， 以 甲醇 为溶剂， 反应 24.0h， 以70%的产率得到5-(3-bromopropyl)-3,3,7,7-tetramethyl[1,2,5]perhydrodithiazepine
  参考文献：
  名称：

  Synthesis of oxorhenium(V) and oxotechnetium(V) [SN(R)S/S] mixed ligand complexes containing a phenothiazine moiety on the tridentate SN(R)S ligand

  摘要：

  Two oxorhenium and two oxotechnetium [SN(R)S/S] mixed ligand complexes bearing the phenothiazine moiety on the tridentate ligand SN(R)S have been synthesized and characterized. The corresponding complexes at tracer level (Tc-99m) have also been prepared. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(01)00309-2

文献信息

• Synthesis of oxorhenium(V) and oxotechnetium(V) [SN(R)S/S] mixed ligand complexes containing a phenothiazine moiety on the tridentate SN(R)S ligand
  作者：Ioannis Pirmettis、Georgios Patsis、Maria Pelecanou、Charalampos Tsoukalas、Apostolos Papadopoulos、Catherine P. Raptopoulou、Aris Terzis、Minas Papadopoulos、Efstratios Chiotellis

  DOI：10.1016/s0960-894x(01)00309-2

  日期：2001.7

  Two oxorhenium and two oxotechnetium [SN(R)S/S] mixed ligand complexes bearing the phenothiazine moiety on the tridentate ligand SN(R)S have been synthesized and characterized. The corresponding complexes at tracer level (Tc-99m) have also been prepared. (C) 2001 Elsevier Science Ltd. All rights reserved.