(1R,4S,5S,8R)-10-methoxy-1,2,3,4,5,6,7,8-octahydro-1,4:5,8-dimethanoanthracene-9-carboxaldehyde | 632367-34-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: (1R,4S,5S,8R)-10-methoxy-1,2,3,4,5,6,7,8-octahydro-1,4:5,8-dimethanoanthracene-9-carboxaldehyde
• CAS: 632367-34-1
• 化学式: C₁₈H₂₀O₂
• 分子量: 268.356
• InChiKey: MEXUEQPGISPTOM-WYUUTHIRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.24
• 重原子数：
  20.0
• 可旋转键数：
  2.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  26.3
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  吡咯 、 (1R,4S,5S,8R)-10-methoxy-1,2,3,4,5,6,7,8-octahydro-1,4:5,8-dimethanoanthracene-9-carboxaldehyde 在 三氟化硼乙醚 、 四氯苯醌 作用下， 生成 meso-tetra-(10-methoxy-bis-methano-octahydroanthracene-9-yl)porphyrin
  参考文献：
  名称：

  Synthesis and catalytic reactivity of sterically and electronically modified D4-symmetric metallotetraarylporphyrins

  摘要：

  Two new sterically-modified and two electronically-modified D-4-symmetrical tetraarylporphyrin ligands have been prepared and the catalytic activity of their manganese complexes in epoxidations of aryl-substituted alkenes studied. Moderate reactivity changes were observed in catalytic epoxdiations with these electronically varied tetraaarylporphyrin complexes, the methoxy derivative giving slightly improved selectivity (83% e.e. with cis-beta-methylstyrene). (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00730-8
• 作为产物：
  描述：

  (1S*,4R*,5R*,8S*)-10-acetoxy-1,2,3,4,5,6,7,8-octahydro-1,4:5,8-dimethanoanthracene-9-carboxaldehyde 在 sodium hydroxide 、 硫酸 、 4-甲基苯磺酸吡啶 、 碳酸氢钠 作用下， 以 四氢呋喃 、 甲醇 、 水 、 苯 为溶剂， 反应 162.0h， 生成 (1R,4S,5S,8R)-10-methoxy-1,2,3,4,5,6,7,8-octahydro-1,4:5,8-dimethanoanthracene-9-carboxaldehyde
  参考文献：
  名称：

  Synthesis and catalytic reactivity of sterically and electronically modified D4-symmetric metallotetraarylporphyrins

  摘要：

  Two new sterically-modified and two electronically-modified D-4-symmetrical tetraarylporphyrin ligands have been prepared and the catalytic activity of their manganese complexes in epoxidations of aryl-substituted alkenes studied. Moderate reactivity changes were observed in catalytic epoxdiations with these electronically varied tetraaarylporphyrin complexes, the methoxy derivative giving slightly improved selectivity (83% e.e. with cis-beta-methylstyrene). (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00730-8

文献信息

• Synthesis and catalytic reactivity of sterically and electronically modified D4-symmetric metallotetraarylporphyrins
  作者：Ronald L. Halterman、Shyi-Tai Jan、Aladamash H. Abdulwali、David J. Standlee

  DOI：10.1016/s0040-4020(97)00730-8

  日期：1997.8

  Two new sterically-modified and two electronically-modified D-4-symmetrical tetraarylporphyrin ligands have been prepared and the catalytic activity of their manganese complexes in epoxidations of aryl-substituted alkenes studied. Moderate reactivity changes were observed in catalytic epoxdiations with these electronically varied tetraaarylporphyrin complexes, the methoxy derivative giving slightly improved selectivity (83% e.e. with cis-beta-methylstyrene). (C) 1997 Elsevier Science Ltd.