Stereochemistry of sulphur organic compounds. Part 11. A conformational study of some 2-thio-derivatives of N-phenyl-1-phenylethylamine
作者:Ernesto Brunet、M. Carmen Carreño、M. Teresa Gallego、José L. García Ruano、Felipe Alcudia
DOI:10.1039/p29830000937
日期:——
The syntheses and a conformational study of N-phenyl-2-Y-1-phenylethylamine [Y = SCH3, SOCH3(two diastereoisomers), SO2CH3, and +S(CH3)2] are reported. Conformational preferences have been established from changes in the vicinal coupling constants induced by protonation at the amine nitrogen. This determines the electrostatic character of the interactions between the two heteroatoms functions. In addition
报道了N-苯基-2-Y-1-苯基乙胺的合成和构象研究[Y = SCH 3,SOCH 3(两个非对映异构体),SO 2 CH 3和+ S(CH 3)2 ]。从在胺氮处质子化引起的邻偶耦合常数的变化已经确定了构象偏好。这确定了两个杂原子功能之间相互作用的静电特性。另外,还报道了非对映异构亚砜的构型分配。