methyl 12-Methyl-12H-dibenzo[d,g][1,3]dioxocin-6-carboxylate | 130072-72-9

• 分子结构分类: 有机化合物 - 苯类化合物
• 英文名称: methyl 12-Methyl-12H-dibenzo[d,g][1,3]dioxocin-6-carboxylate
• 英文别名: Methyl-6-Methyl-12H-Dibenzo[d,g][1,3]dioxocin-6-carboxylate；methyl 5-methyl-5H-benzo[d][1,3]benzodioxocine-11-carboxylate
• CAS: 130072-72-9
• 化学式: C₁₇H₁₆O₄
• 分子量: 284.312
• InChiKey: LWIANVLGNVRSDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  21
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  二氯乙酸 、 1,1-双(2-羟基苯基)乙烷 在 potassium iodide 、 potassium carbonate 作用下， 生成 methyl 12-Methyl-12H-dibenzo[d,g][1,3]dioxocin-6-carboxylate
  参考文献：
  名称：

  Herbicidal 12-substituted 12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic

  摘要：

  二苯并[d,g][1,3]二噁喃-6-羧酸在12位被甲基或乙基或一种基团--CH.sub.2 CH.sub.2--取代，并且在其他位置可选择性地被取代，例如甲基4'-氯螺(cyclopropane-1,12'(12'H)-dibenzo[d,g][1,3]二噁喃)-6'-羧基酸，以及它们的农业可接受的酯、酰胺和盐对于控制不良植被是有用的。用于螺环丙烷化合物的1,1-二芳基环丙烷中间体可以通过与苯硫甲基锂试剂反应制备，该试剂由适当取代的1,1-二芳基乙烯前体制备而成。

  公开号：

  US04938790A1

文献信息

• Herbicidal and plant growth regulant activity of glyoxylates
  申请人：Fermenta ASC Corporation

  公开号：US04976770A1

  公开（公告）日：1990-12-11

  12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic acid and certain derivatives thereof (glyoxylates) exhibit plant growth regulant and herbicidal activity when applied to a plant locus.

  12H-二苯并[d,g][1,3]二噁英-6-羧酸及其某些衍生物（乙二醛酸）在施加到植物位点时表现出植物生长调节剂和除草剂活性。
• Herbicidal 12-substituted 12H-dibenzo[d,g]dioxocin-6-carboxylic acids
  申请人：The Dow Chemical Company

  公开号：US05158597A1

  公开（公告）日：1992-10-27

  Dibenzo[d,g][1,3]dioxocin-6-carboxylic acids substituted by methyl or ethyl or a moiety --CH.sub.2 CH.sub.2 -- at the 12-position and optionally substituted at other positions, such as methyl 4'-chlorospiro(cyclopropane-1,12'(12'H)-dibenzo[d,g][1,3]dioxocin)-6'-carb oxylic acid, and their agriculturally acceptable esters, amides, and salts are useful for the control of undesirable vegetation. The 1,1-diarylcyclopropane intermediates required for the spirocyclopropane compounds can be prepared from appropriately substituted 1,1-diarylethene procursors by reaction with phenylthiomethyl lithium reagent.

  甲基或乙基或一个基团--CH.sub.2 CH.sub.2 --取代的Dibenzo[d,g][1,3]二噁烷-6-羧酸以及其在其他位置如甲基4'-氯代螺环丙烷-1,12'(12'H)-dibenzo[d,g][1,3]二噁烷)-6'-羧酸中的取代物，以及它们的农业可接受的酯，酰胺和盐对于控制不良的植被是有用的。制备螺环丙烷化合物所需的1,1-二芳基环丙烷中间体可以通过与苯硫甲基锂试剂反应的适当取代的1,1-二芳基乙烯前体制备。
• Method of preparing bis-phenol ethers
  申请人：The Dow Chemical Company

  公开号：US04999448A1

  公开（公告）日：1991-03-12

  A method of preparing a compound of Formula XII ##STR1## wherein R.sub.1 and R.sub.2 together represent the fragment --Ch.sub.2 CH.sub.2 --; each R.sup.4 independently represents C.sub.1 -C.sub.4 alkyl optionally substituted with 1 to 2 C.sub.1 -C.sub.4 alkoxy groups; and X, X', Y, Y', Z, and Z' each, independently represent H, F, Cl, Br, I, CN, NO.sub.2, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, phenoxy, C.sub.1 -C.sub.4 alkylthio, phenylthio, or C.sub.1 -C.sub.4 dialkylamino, wherein each alkyl, alkoxy, and alkylthio group is optionally substituted with one or more compatible groups selected from C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, F, Cl, Br, CN, and phenyl and wherein each phenyl group is optionally substituted with up to 3 groups selected from F, Cl, Br, CN, CF.sub.3, C.sub.1 -C.sub.4 alkyl, and C.sub.1 -C.sub.4 alkoxy.

  一种制备式为XII的化合物的方法：##STR1## 其中R.sub.1和R.sub.2一起代表--Ch.sub.2 CH.sub.2--；每个R.sup.4独立地代表C.sub.1-C.sub.4烷基，可选择地取代1至2个C.sub.1-C.sub.4烷氧基；而X、X'、Y、Y'、Z和Z'各自独立地代表H、F、Cl、Br、I、CN、NO.sub.2、C.sub.1-C.sub.4烷基、C.sub.1-C.sub.4烷氧基、苯氧基、C.sub.1-C.sub.4烷基硫醚、苯基硫醚或C.sub.1-C.sub.4二烷基氨基，其中每个烷基、烷氧基和烷基硫醚基可选择地取代一个或多个与C.sub.1-C.sub.4烷氧基、C.sub.1-C.sub.4烷基硫醚基、F、Cl、Br、CN和苯基相容的基团，而每个苯基可选择地取代最多3个F、Cl、Br、CN、CF.sub.3、C.sub.1-C.sub.4烷基和C.sub.1-C.sub.4烷氧基。
• Herbicidal 12-substituted 12H-dibenzo[d,g][1,3]dioxocin-6-carboxylic
  申请人：The Dow Chemical Company

  公开号：US05071465A1

  公开（公告）日：1991-12-10

  Dibenzo[d,g][1,3]dioxocin-6-carboxylic acids substituted by methyl or ethyl or a moiety --CH.sub.2 CH.sub.2 -- at the 12-position and optionally substituted at other positions, such as methyl 4'-chlorospiro(cyclopropane-1,12'(12'H)-dibenzo[d,g][1,3]dioxocin)-6'-carb oxylic acid, and their agriculturally acceptable esters, amides, and salts are useful for the control of undesirable vegetation. The 1,1-diarylcyclopropane intermediates required for the spirocyclopropane compounds can be prepared from appropriately substituted 1,1-diarylethene procursors by reaction with phenylthiomethyl lithium reagent.

  甲基或乙基或一个基团--CH.sub.2 CH.sub.2 --置于12位，并在其他位置可选择性地置换的二苯并[d,g][1,3]二噁烷-6-羧酸，例如甲基4'-氯螺[cyclopropane-1,12'(12'H)-二苯并[d,g][1,3]二噁烷]-6'-羧酸及其农业上可接受的酯，酰胺和盐，可用于控制不良杂草。制备螺环丙烷化合物所需的1,1-二芳基环丙烷中间体可以通过与苯基硫甲基锂试剂反应的适当取代的1,1-二芳基乙烯前体制备。
• 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation
  申请人：DowElanco

  公开号：EP0403026A1

  公开（公告）日：1990-12-19

  Dibenzo[d,g][1,3]dioxocin-6-carboxylic acids substituted by methyl or ethyl or a moiety -CH₂CH₂- at the 12-position and optionally substituted at other positions, such as methyl 4′-chlorospiro(cyclopropane-­1,12′(12′H)-dibenzo[d,g][1,3]dioxocin)-6′-carboxylic acid, and their agriculturally acceptable esters, amides, and salts are useful for the control of undesirable vegetation. The 1,1-diarylcyclopropane intermediates required for the spirocyclopropane compounds can be prepared from appropriately substituted 1,1-diarylethene procursors by reaction with phenylthiomethyl lithium reagent.

  二苯并[d,g][1,3]二氧杂环辛-6-羧酸，在 12 位被甲基或乙基或分子-CH₂CH₂-取代，并可选择在其他位置被取代，例如甲基 4′-氯螺(环丙烷-1、12′(12′H)-二苯并[d,g][1,3]二氧杂环辛)-6′-羧酸及其农业上可接受的酯、酰胺和盐类可用于控制不良植被。螺环丙烷化合物所需的 1,1-二芳基环丙烷中间体可通过与苯硫甲基锂试剂反应，从适当取代的 1,1-二芳基烯原体中制备。