2,3-dipyridin-2-yl-1,4,5,12-tetraazatriphenylene | 7756-04-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 2,3-dipyridin-2-yl-1,4,5,12-tetraazatriphenylene
• 英文别名: 2,3-di-pyridin-2-yl-pyrazino[2,3-f][4,7]phenanthroline；2,3-Bis-(2)-pyridyl-dipyrido<2,3-f:3',2'-h>-chinoxalin；2,3-Dipyridin-2-ylpyrazino[2,3-f][4,7]phenanthroline；2,3-dipyridin-2-ylpyrazino[2,3-f][4,7]phenanthroline
• CAS: 7756-04-9
• 化学式: C₂₄H₁₄N₆
• 分子量: 386.415
• InChiKey: TYERBOSRLSZOAB-UHFFFAOYSA-N

物化性质

• 熔点：
  >360 °C
• 沸点：
  616.0±50.0 °C(Predicted)
• 密度：
  1.371±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  30
• 可旋转键数：
  2
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  77.3
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  泛喹酮 在 palladium on activated charcoal 盐酸羟胺 、 一水合肼 、 barium carbonate 作用下， 以 乙醇 为溶剂， 反应 23.0h， 生成 2,3-dipyridin-2-yl-1,4,5,12-tetraazatriphenylene
  参考文献：
  名称：

  Efficient Synthesis of 1,4,5,12-Tetraazatriphenylene and Derivatives

  摘要：

  Condensation of 5,6-diamino-4,7-phenanthroline with glyoxal provides 1,4,5,12-tetraazatriphenylene in quantitative yield. This procedure avoids the 50% loss of product inherent in previous methods. Derivatives were also prepared by using alpha-dicarbonyl compounds other than glyoxal. Additional derivatives were prepared from 1,4,5,12-tetraazatriphenylene-2,3-dicarbonitrile, produced by condensation of diaminomaleonitrile with 4,7-phenanthroline-5,6-dione.

  DOI：

  10.1021/jo0495283

文献信息

• Efficient Synthesis of 1,4,5,12-Tetraazatriphenylene and Derivatives
  作者：Chandima Abeywickrama、Arthur David Baker

  DOI：10.1021/jo0495283

  日期：2004.10.1

  Condensation of 5,6-diamino-4,7-phenanthroline with glyoxal provides 1,4,5,12-tetraazatriphenylene in quantitative yield. This procedure avoids the 50% loss of product inherent in previous methods. Derivatives were also prepared by using alpha-dicarbonyl compounds other than glyoxal. Additional derivatives were prepared from 1,4,5,12-tetraazatriphenylene-2,3-dicarbonitrile, produced by condensation of diaminomaleonitrile with 4,7-phenanthroline-5,6-dione.