(4-methoxymethylphenyl)diphenylphosphane | 35542-35-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-methoxymethylphenyl)diphenylphosphane
• 英文别名: (p-Methoxymethyl-phenyl)-diphenyl-phosphin；(p-Diphenyl-phosphinobenzyl)-methylaether；[4-(Methoxymethyl)phenyl]-diphenylphosphane
• CAS: 35542-35-9
• 化学式: C₂₀H₁₉OP
• 分子量: 306.344
• InChiKey: IVBQNLILBSXAQI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (4-methoxymethylphenyl)diphenylphosphane 在 盐酸 作用下， 生成 p-Diphenylphosphinobenzylchlorid
  参考文献：
  名称：

  Substituenteneinfluss der phosphino- und der phosphinylgruppe auf die reaktivität aromatischer verbindungen—I

  摘要：

  DOI：

  10.1016/s0040-4020(01)93779-2
• 作为产物：
  描述：

  4-溴基苄基甲醚 、 二苯基氯化膦 在 正丁基锂 作用下， 以 四氢呋喃 为溶剂， 反应 0.5h， 以91%的产率得到(4-methoxymethylphenyl)diphenylphosphane
  参考文献：
  名称：

  Polymeric Phosphine Ligand from Ring-Opening Metathesis Polymerization of a Norbornene Derivative. Applications in the Heck, Sonogashira, and Negishi Reactions

  摘要：

  The phosphine-containing polymer 1 is obtained by ruthenium-catalyzed ring-opening metathesis polymerization of the norbornene derivative 2. Polymer 1 is employed as the polymer support in the palladium-catalyzed Heck, Sonogashira, and Negishi reactions, and the corresponding (methoxymethylphenyl)diphenylphosphine (6) ligand is used for comparison. The polymer-supported catalysts retain most of their catalytic activities in these coupling reactions in the recycling processes.

  DOI：

  10.1021/jo035318z

文献信息

• Polymeric Phosphine Ligand from Ring-Opening Metathesis Polymerization of a Norbornene Derivative. Applications in the Heck, Sonogashira, and Negishi Reactions
  作者：Yun-Chin Yang、Tien-Yau Luh

  DOI：10.1021/jo035318z

  日期：2003.12.1

  The phosphine-containing polymer 1 is obtained by ruthenium-catalyzed ring-opening metathesis polymerization of the norbornene derivative 2. Polymer 1 is employed as the polymer support in the palladium-catalyzed Heck, Sonogashira, and Negishi reactions, and the corresponding (methoxymethylphenyl)diphenylphosphine (6) ligand is used for comparison. The polymer-supported catalysts retain most of their catalytic activities in these coupling reactions in the recycling processes.
• Substituenteneinfluss der phosphino- und der phosphinylgruppe auf die reaktivität aromatischer verbindungen—I
  作者：B. Klabuhn、H. Goetz、P. Steirl、D. Alscher

  DOI：10.1016/s0040-4020(01)93779-2

  日期：1976.1